GSK2837808A is a potent, selective lactate dehydrogenase A (LDHA) inhibitor (IC50 values are 1.9 and 14 nM for LDHA and LDHB respectively).
For research use only. We do not sell to patients.
| Name | GSK2837808A | 
|---|---|
| Iupac Chemical Name | 3-[[3-[(cyclopropylamino)sulfonyl]-7-(2,4-dimethoxy-5-pyrimidinyl)-4-quinolinyl]amino]-5-(3,5-difluorophenoxy)-benzoic acid | 
| Synonyms | GSK2837808A; GSK-2837808A; GSK 2837808A; GSK2837808; GSK-2837808; GSK 2837808. | 
| Molecular Formula | C31H25F2N5O7S | 
| Molecular Weight | 649.6258 | 
| Smile | O=C(O)C1=CC(OC2=CC(F)=CC(F)=C2)=CC(NC3=C(S(=O)(NC4CC4)=O)C=NC5=CC(C6=CN=C(OC)N=C6OC)=CC=C35)=C1 | 
| InChiKey | RZBCPMYJIARMGV-UHFFFAOYSA-N | 
| InChi | InChI=1S/C31H25F2N5O7S/c1-43-29-25(14-35-31(37-29)44-2)16-3-6-24-26(9-16)34-15-27(46(41,42)38-20-4-5-20)28(24)36-21-7-17(30(39)40)8-22(13-21)45-23-11-18(32)10-19(33)12-23/h3,6-15,20,38H,4-5H2,1-2H3,(H,34,36)(H,39,40) | 
| CAS Number | 1445879-21-9 | 
| Related CAS | 
| Packaging | Price | Availability | Purity | Shipping Time | 
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry | 
| Formulation | Off-white solid to white solid | 
|---|---|
| Purity | >98% | 
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). | 
| Solubility | Soluble in DMSO | 
| Handling | |
| Shipping Condition | Shipped under ambient temperature | 
| HS Code | 
| Targets | |
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| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |