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SLx-2119

Catalog No.: 91002
Cas No.: 911417-87-3
Purity : 98% 
91002 - SLx-2119 | CAS 911417-87-3

Catalog number : 91002

CAS number : 911417-87-3

Molecular Formula : C26H24N6O2 

Molecular Weight : 452.51 

Iupac Chemical Name : 2-(3-(4-((1H-indazol-5-yl)amino)quinazolin-2-yl)phenoxy)-N-isopropylacetamide 

Smile : N1N=CC2=CC(=CC=C12)NC1=NC(=NC2=CC=CC=C12)C=1C=C(OCC(=O)NC(C)C)C=CC1

InChiKey : GKHIVNAUVKXIIY-UHFFFAOYSA-N

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SynonymsSLx 2119;SLx2119;ROCK inhibitor;KD-025 
Molecular FormulaC26H24N6O2 
Molecular Weight452.51 
AppearanceSolid powder 
Purity98% 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
SmileN1N=CC2=CC(=CC=C12)NC1=NC(=NC2=CC=CC=C12)C=1C=C(OCC(=O)NC(C)C)C=CC1
InChiKeyGKHIVNAUVKXIIY-UHFFFAOYSA-N
InChiInChI=1S/C26H24N6O2/c1-16(2)28-24(33)15-34-20-7-5-6-17(13-20)25-30-23-9-4-3-8-21(23)26(31-25)29-19-10-11-22-18(12-19)14-27-32-22/h3-14,16H,15H2,1-2H3,(H,27,32)(H,28,33)(H,29,30,31)
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SLx-2119(KD-025) is a small molecule and selective inhibitor of ROCK2 with IC50 of 105 nM; > 200 fold selecivity over ROCK1(IC50 =24 uM). 

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