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GDC-0927

Catalog No.: 1811301
Cas No.: 1642297-01-5
Purity : >98%
1811301 - GDC-0927 | CAS 1642297-01-5

Catalog number : 1811301

CAS number : 1642297-01-5

Molecular Formula : C28H28FNO4

Molecular Weight : 461.53

Iupac Chemical Name : (2S)-2-(4-{2-[3-(Fluoromethyl)-1-azetidinyl]ethoxy}phenyl)-3-(3-hydroxyphenyl)-4-methyl-2H-chromen-6-ol

Smile : OC1=CC(C(C)=C(C2=CC=CC(O)=C2)[C@H](C3=CC=C(OCCN4CC(CF)C4)C=C3)O5)=C5C=C1

InChiKey : KJAAPZIFCQQQKX-NDEPHWFRSA-N

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SynonymsGDC-0927; GDC 0927; GDC0927; SRN-927; SRN 927; SRN927.
Molecular FormulaC28H28FNO4
Molecular Weight461.53
AppearanceOff-white solid to white solid
Purity>98%
SolubilitySoluble in DMSO
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Shipping ConditionShipped under ambient temperature
SmileOC1=CC(C(C)=C(C2=CC=CC(O)=C2)[C@H](C3=CC=C(OCCN4CC(CF)C4)C=C3)O5)=C5C=C1
InChiKeyKJAAPZIFCQQQKX-NDEPHWFRSA-N
InChiInChI=1S/C28H28FNO4/c1-18-25-14-23(32)7-10-26(25)34-28(27(18)21-3-2-4-22(31)13-21)20-5-8-24(9-6-20)33-12-11-30-16-19(15-29)17-30/h2-10,13-14,19,28,31-32H,11-12,15-17H2,1H3/t28-/m0/s1
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GDC-0927, also known as SRN-927, is a next-generation oral SERD which appears to have greater potential than GDC-0810 to be a best-in-class SERD molecule.

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