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MAPK
Cytoskeletal Signaling
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
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Cas Index 1
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Cas Index 1
1443978-76-4 | ethyl 4-hydroxy-6-methylpyrazolo[1,5-a]pyrazine-2-carboxylate
(Catalog# : 20360)
1449598-75-7 | ethyl 4-chloro-6-methylpyrazolo[1,5-a]pyrazine-2-carboxylate
(Catalog# : 20359)
1449598-76-8 | ethyl 4,6-dimethylpyrazolo[1,5-a]pyrazine-2-carboxylate
(Catalog# : 20358)
1174046-84-4 | Ethyl 4-Ethoxy-2-oxo-1,2-dihydropyridine-3-carboxylate
(Catalog# : 20327)
190133-94-9 | Ecopipam hydrochloride ( SCH-39166 )
(Catalog# : 20296)
Ecopipam HCl is a Selective Dopamine Receptor D1/D5 Antagonist used in the treatment
1219925-73-1 | E6446
(Catalog# : 21240)
1884461-72-6 | Ensifentrine ( RPL554 )
(Catalog# : 61726)
Ensifentrine (RPL554) is an investigational, first-in-class, inhaled dual inhibitor o
1262132-81-9 | Enarodustat ( JTZ-951 )
(Catalog# : 2073104)
Enarodustat ( JTZ-951 ) is an orally-active HIF-PH inhibitor with an EC50 of 0.22 Μm
1443763-60-7 | Empesertib
(Catalog# : 2071554)
Empesertib, also known as BAY1161909, is an orally bioavailable, selective inhibitor
1839150-63-8(溴化物 | EB-3D
(Catalog# : 2061302)
EB-3D is a novel potent and selective choline kinase ChoKα inhibitor. EB-3D Induces
1809885-32-2 | EC-5026
(Catalog# : 2051508)
EC5026, also known as BPN-19186, is a first-in-class, potent and orally active solubl
1092977-06-4 | Evenamide HCl
(Catalog# : 112594)
Evenamide HCl ( CAS 1092977-06-4) ,a sodium channel blocker, shows efficacy in a broa
1092977-61-1 | Evenamide
(Catalog# : 112593)
venamide is a sodium and/or calcium channel modulator. Evenamide may be potentia usef
182567-89-1 | ethyl 2-acetyl-4-bromobenzoate
(Catalog# : 95071)
ethyl 2-acetyl-4-bromobenzoate;2-ACETYL-4-BROMOBENZOIC ACID ETHYL ESTER
153832-46-3 | Ertapenem
(Catalog# : 19318)
Ertapenem is a parenteral carbapenem that is highly resistant to inactivation by a wi
133040-01-4 | Eprosartan
(Catalog# : 192182)
Eprosartan is a competitive and reversible angiotensin II receptor antagonist used fo
1219739-36-2 | EX-229 free acid
(Catalog# : 192153)
EX-229, also known as AMPK Activator 991, is a novel AMPK activator, increasing AMPK
1369489-71-3 | E7046
(Catalog# : 191101)
E7046 is a potent and selective antagonist of the type 4 prostaglandin E2 (PGE2) rece
143851-98-3 | Elacridar HCl
(Catalog# : 19121)
Elacridar, also known as GF120918A, is a P-glycoprotein (P-gp) inhibitor, and has bee
1181770-72-8 | EMD638683
(Catalog# : 1810253)
EMD638683 is a potent inhibitor of SGK1 with an IC50 value of 3 μM.
189453-10-9 | Epothilone D
(Catalog# : 186292)
Epothilone D is a natural polyketide compound isolated from the myxobacterium Sorangi
1628830-21-6 | EZM2302
(Catalog# : 186272)
EZM2302 is a potent, selective, and orally available arginine methyltransferase CARM1
169869-90-3 | Exatecan mesylate
(Catalog# : 186271)
Exatecan, also known as DX 8951, is semisynthetic, water-soluble camptothecin derivat
164650-44-6 | Efinaconazole
(Catalog# : 186213)
Efinaconazole is a triazole antifungal. It is approved for use in Canada and the USA
1197194-61-8 | Endoxifen E-isomer HCl
(Catalog# : 184124)
Endoxifen E-isomer is a tamoxifen metabolite and potent Selective Estrogen Response M
1370651-20-9 | Ensartinib ( X396 )
(Catalog# : 184321)
Ensartinib is an orally available small molecule inhibitor of the receptor tyrosine k
1914078-41-3 | eCF506 ( NXP 900 )
(Catalog# : 18382)
eCF506 targets a molecule called Src tyrosine kinase that is required for breast canc
1632006-28-0 | Esaxerenone
(Catalog# : 1710121)
Esaxerenone (INN) (developmental code names CS-3150, XL-550) is a nonsteroidal antimi
1616391-65-1 | EPZ015666
(Catalog# : 011309)
EPZ015666 is a potent, selective and orally bioavailable PRMT5 inhibitor with Ki of 5
1346242-81-6 | Erdafitinib(JNJ-42756493)
(Catalog# : 651701)
Erdafitinib(JNJ-42756493)is a potent and selective orally bioavailable, pan fibroblas
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
1393466-87-9 | PLX8394
(Catalog# : 20613)
PLX8394 is an orally bioavailable inhibitor of serine/threonine-protein kinase B-raf
2365193-22-0 | Zelasudil
(Catalog# : 24014)
Zelasudil is a potent, highly selective and orally-active inhibitor that targets Rho-
2134675-36-6 | Ziftomenib ( KO-539 )
(Catalog# : 24013)
Ziftomenib is an oral, potent, and selective small molecule inhibitor that targets th
1640282-42-3 | Zunsemetinib
(Catalog# : 24012)
Zunsemetinib is an investigational oral mitogen-activated protein kinase-activated pr
2728667-27-2 | Zongertinib
(Catalog# : 24011)
Zongertinib [BI 1810631] is a human epidermal growth factor receptor 2 (HER2) inhibit
2272904-53-5 | Zasocitinib
(Catalog# : 24010)
Zasocitinib is under development for the treatment of moderate to severe plaque psori
2503036-46-0 | RNK-05047
(Catalog# : 24008)
RNK-05047 is a PROTAC degrader of BRD4 which displays significant tumor growth inhibi
1001288-58-9 | Asengeprast (FT011)
(Catalog# : 24009)
Asengeprast (FT011) is an anti-fibrotic agent thatreduces mRNA expression of collagen
2490431-16-6 | ERAS-801 ( JGK-068S )
(Catalog# : 20635)
ERAS-801 ( JGK-068S ) is a potent EGFR inhibitor.
209746-59-8 | T-1095
(Catalog# : 24004)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).