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PTC124c

Catalog No.: 52231
Cas No.: 775304-57-9
Purity : 98% 
52231 - PTC124c | CAS 775304-57-9

Catalog number : 52231

CAS number : 775304-57-9

分子式 : C15H9FN2O3 

分子量 : 284.24 

化学名称 : PTC124c

Smile : c1ccc(c(c1)c2nc(no2)c3cccc(c3)C(=O)O)F

InChiKey : OOUGLTULBSNHNF-UHFFFAOYSA-N

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分子式C15H9FN2O3 
分子量284.24 
纯度98% 
Smilec1ccc(c(c1)c2nc(no2)c3cccc(c3)C(=O)O)F
InChiKeyOOUGLTULBSNHNF-UHFFFAOYSA-N
InChiInChI=1S/C15H9FN2O3/c16-12-7-2-1-6-11(12)14-17-13(18-21-14)9-4-3-5-10(8-9)15(19)20/h1-8H,(H,19,20)
MDLMFCD09864996
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PTC124 (Ataluren) selectively induces ribosomal read-through of premature but not normal termination codons, with EC50 of 0.1 M, may provide treatment for genetic disorders caused by nonsense mutations (e.g. CF caused by CFTR nonsense mutation). 

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