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AZ3146

Catalog No.: 51903
Cas No.: 1124329-14-1
Purity : 98% 
51903 - AZ3146 | CAS 1124329-14-1

Catalog number : 51903

CAS number : 1124329-14-1

分子式 : C24H32N6O3 

分子量 : 452.55 

Iupac 化学名称 : 9-cyclopentyl-2-(2-methoxy-4-(1-methylpiperidin-4-yloxy)phenylamino)-7-methyl-7H-purin-8(9H)-one 

Smile : C1(CCCC1)N1C2=NC(=NC=C2N(C1=O)C)NC1=C(C=C(C=C1)OC1CCN(CC1)C)OC

InChiKey : YUKWVHPTFRQHMF-UHFFFAOYSA-N

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同义词AZ3146;AZ-3146 
英文同义词AZ3146;AZ-3146 
分子式C24H32N6O3 
分子量452.55 
外观off-white solid 
纯度98% 
可溶性5mg/ml in DMSO 
存储3 years -20ºCpowder 6 months-80ºCin solvent 
运输条件Shipped under ambient temperature. 
SmileC1(CCCC1)N1C2=NC(=NC=C2N(C1=O)C)NC1=C(C=C(C=C1)OC1CCN(CC1)C)OC
InChiKeyYUKWVHPTFRQHMF-UHFFFAOYSA-N
InChiInChI=1S/C24H32N6O3/c1-28-12-10-17(11-13-28)33-18-8-9-19(21(14-18)32-3)26-23-25-15-20-22(27-23)30(24(31)29(20)2)16-6-4-5-7-16/h8-9,14-17H,4-7,10-13H2,1-3H3,(H,25,26,27)
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AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM, contributes to recruitment of CENP-E (kinesin-related motor protein), less potent to FAK, JNK1, JNK2, and Kit. 

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