AGI-6780 is the first highly potent and selective small molecule inhibitor of isocitrate dehydrogenases, which binds in an allosteric manner at the dimer interface of mutant IDH2-R140Q (IC50=23 nM)
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化学信息
| 名称 | AGI-6780 |
| 分子式 | C21H18F3N3O3S2 |
| 分子量 | 481.51 |
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| Cas号 | 1432660-47-3 |
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