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+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
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Immunology & Inflammation
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MAPK
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Cas号索引 8
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Cas号索引 8
845932-30-1 | KU59403
(Catalog# : 19123)
KU59403是一种有效的选择性ATM(共济失调毛细血管扩张突变)抑制剂,
853299-07-7 | K03861
(Catalog# : 611921)
K03861 is a type II CDK2 inhibitor with Kd of 8.2 nM.K03861 inhibits CDK2 activity by
819812-04-9 | KW-2478
(Catalog# : 121431)
KW-2478 是一种针对人类热休克蛋白 90 (Hsp90) 的药物,具有潜在的抗
849776-05-2 | Ladarixin
(Catalog# : 24039)
Ladarixin(DF-2156;DF-2156A)是一种口服活性、变构非竞争性和双CXCR
878672-00-5 | 雷西那德
(Catalog# : 17022706)
雷西那德(RDEA594),是URAT1的一日一次抑制剂,是肾脏中调节尿酸排泄
892128-60-8 | LY2334737
(Catalog# : 16123040)
LY2334737 is an orally available valproic acid ester of gemcitabine, a broad-spectrum
847871-99-2 | Lenalidomide hemihydrate
(Catalog# : 6111409)
Lenalidomide (Revlimid, CC-5013) is a TNF- secretion inhibitor with IC50 of 13 nM.Len
867160-71-2 | Linsitinib
(Catalog# : 010819)
Linsitinib is highly potent, orally efficacious and highly selective, dual ATP-compet
862507-23-1 | LY2228820
(Catalog# : 122509)
LY2228820 is a novel and potent p38MAPK inhibitor (the IC50 for p38MAPK and p38MAPK w
891016-02-7 | ML-SI3
(Catalog# : 20287)
ML-SI3 is a chemical compound which acts as an "antagonist" (i.e. channel b
838810-96-1 | MAC-545496
(Catalog# : 2071611)
MAC-545496 is potent GraR inhibitor (glycopeptide-resistance-associated protein R). M
877636-42-5 | ML221
(Catalog# : 19311)
ML221是apelin (APJ)受体的拮抗剂。
869901-69-9 | MK-2048
(Catalog# : 181251)
MK-2048是第二代HIV-1整合酶抑制剂。
847163-28-4 | ML 351
(Catalog# : 1811282)
ML 351是一种选择性的12/15 LOX抑制剂,在体内具有活性。
869363-13-3 | MLN8054
(Catalog# : 18742)
MLN8054是一种MLN8054的极光激酶抑制剂,它是一种口服的生物活性药
825658-06-8 | ML335
(Catalog# : 184216)
ML335 is a potent and selective TREK-1/2 Activator. ML335 is an agonist for OPRM1-OPR
846557-71-9 | ML-385
(Catalog# : 179119)
ML-385是强有力的和有选择性的Nrf2抑制剂(IC50 = 1.9μNrf2;M)。ML-3
878978-76-8 | ML-098
(Catalog# : 17030910)
ML-098, 也叫 CID- 7345532,是GTP结合蛋白Rab7(EC50 = 77.6 nM)的激活剂。
899713-86-1 | ML348
(Catalog# : 17030712)
ML348,又称CID 3238952;SID 160654487,是一个可逆的LYPLA1抑制剂,IC50值
863971-19-1 | Mafodotin
(Catalog# : 16122831)
Mafodotin, also known as mc-MMAF and SGD-1269 or Maleimidocaproyl monomethylauristati
862189-95-5 | Mirodenafil
(Catalog# : 030904)
Coming soon!
897657-95-3 | MSX-122
(Catalog# : 011906)
MSX-122 is a n orally bioavailable inhibitor of CXCR4 with potential antineoplastic a
852536-39-1 | ME-143
(Catalog# : 011902)
ME -143 is a derivative of triphendiol and is a highly potent, pan acting ant-cancer.
86347-15-1 | Medetomidine hydrochloride
(Catalog# : 010606)
Medetomidine Hydrochloride is an agonist of adrenergic alpha-2 receptor, which is use
870005-19-9 | MK-2048
(Catalog# : 010424)
MK-2048 is a second generation integrase inhibitor, intended to be used against HIV i
885325-71-3 | MK8745
(Catalog# : 122819)
MK-8745 is a novel Aurora-A specific inhibitor. MK8745 induced apoptotic cell death i
875337-44-3 | MGCD-265-analog
(Catalog# : 111013)
MGCD-265-analogis a tyrosine kinase inhibitor that selectively targets MET and Axl.MG
88191-84-8 | MDL 28170
(Catalog# : 102610)
MDL 28170 is a potent, cell-permeable, and selective inhibitor of calpain and catheps
85278-24-6 | MDL72274(HCl)
(Catalog# : 90301A)
MDL72274 is a specific semicarbazide-sensitive amine oxidase (SSAO) inhibitor.
857876-30-3 | Motesanib Diphosphate (AMG-706)
(Catalog# : 52101)
Motesanib Diphosphate (AMG-706) is a potent ATP-competitive inhibitor ofVEGFR1/2/3wit
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产品分类
信号通路
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
----
NEKs
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
----
GLP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
----
Lactate dehydrogenase
----
Glyoxalase (GLO)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
1497439-74-3 | AD-8007
(Catalog# : 26A018)
AD-8007是一种选择性且可穿透血脑屏障的乙酰辅酶A合成酶2(ACSS2)
1802650-31-2 | ZY-444
(Catalog# : 26A020)
ZY-444是一种通过抑制PC活性发挥抗癌作用的药物。
2306525-79-9 | AD-5584
(Catalog# : 26A019)
AD-5584是一种新型脑渗透性ACSS2抑制剂。
3079716-11-0 | IDB-003
(Catalog# : 26A017)
IDB-003在体内抑制MDA-MB-231肿瘤生长。
1357362-02-7 | Vafidemstat
(Catalog# : 18891)
Vafidemstat又称ORY 2001,是一种赖氨酸特异性组蛋白去甲基化酶(LSD1)
1260247-42-4 | LLL12
(Catalog# : 25075)
LLL12是一种强效的STAT3抑制剂。LLL12在小鼠异种移植物模型中显示出
2758659-09-3 | ECC-5004
(Catalog# : 26A015)
ECC5004是一款每日一次、低剂量、小分子GLP-1受体激动剂。
2911585-37-8 | SILA-123
(Catalog# : 26A014)
SILA-123是一种II型FLT3抑制剂,对FLT3-WT(IC50=2.1 nM)和FLT3-ITD(IC50=1
1214922-52-7 | Encaleret sulfate
(Catalog# : 26A013)
Encaleret是一种正在研究的钙敏感受体的小分子拮抗剂,用于钙稳态
1431303-72-8 | Iadademstat ( ORY-1001 ) hydrochloride
(Catalog# : 26A011)
Iadademstat(ORY-1001)是一种口服活性、高效和选择性的表观遗传酶