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Cas号索引 8
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Cas号索引 8
827318-97-8 | 达鲁舍替
(Catalog# : 1781107)
达鲁舍替,也称为PHA-739358,是一种小分子3 -氨基吡唑衍生物,具
863774-58-7 | Dimethylenastron
(Catalog# : 16122932)
Dimethylenastron is an inhibitor of mitotic motor kinesin Eg5 (IC50 = 200 nM). Dimeth
850876-88-9 | Danoprevir
(Catalog# : 16070107)
Danoprevir, also known as ITMN-191 and RG-7227, is under development by InterMune Inc
852329-66-9 | Dutogliptin
(Catalog# : 011113)
Dutogliptin is a potent, water soluble, selective and orally bioavailable, boronic ac
847499-27-8 | Delanzomib
(Catalog# : 111302)
Delanzomib is a novel orally-active inhibitor of the chymotrypsin-like activity of th
862574-88-7 | 1-(2,2-Difluorobenzo[1,3]dioxol-5-yl)-cyclopropanecarboxylic acid
(Catalog# : 92211)
Coming soon!
84315-24-2 | 3-(3,5-Difluorophenyl)propionic acid
(Catalog# : 90616)
Coming soon!
89180-50-7 | 5,6-Dichloropyridazin-4-amine
(Catalog# : 81006)
Coming soon!
866405-64-3 | Dorsomorphin
(Catalog# : 52744)
Dorsomorphin(Compound C; BML-275) has been shown to act as a potent and selective inh
89464-63-1 | DMOG
(Catalog# : 52236)
Dimethyloxallyl Glycine(DMOG) is a cell permeable, competitive inhibitor of HIF-PH(HI
82304-99-2 | 3-甲酰基-4-羟基苯甲酸乙酯
(Catalog# : 20366)
870843-42-8 | E2012
(Catalog# : 1810231)
E2012是γ-secretase分泌酶调制器(GSM)。
848193-68-0 | EX-527 S-enantiomer
(Catalog# : 17011802)
EX-527 S-enantiomer是一种有效的选择性SIRT1抑制剂,IC50为123 nM;没有对
848193-69-1 | EX-527 R-enantiomer
(Catalog# : 17011801)
EX-527 R-enantiomer是对活性形式EX-527 S-enantiomer(推测为参考)的负控制
828934-41-4 | Etomoxir钠盐
(Catalog# : 17011103)
Etomoxir是一种在线粒体内膜的外表面的一种不可逆转的CPT-1抑制剂
858668-07-2 | EMD534085
(Catalog# : 16122938)
EMD534085 is a kinesin inhibitor currently in clinical development.
864821-90-9 | Eluxadoline
(Catalog# : 012005)
Eluxadoline is an orally active mixed opioid receptor (OR) agonist opioid receptor
834153-87-6 | Elagolix
(Catalog# : 121413)
Elagolix is a Gonadotropin-Releasing Hormone (GnRH) Antagonist.
866588-11-6 | Ethyl 3-(4-fluorophenyl)-1H-pyrazole-5-carboxylate
(Catalog# : 91707)
Coming soon!
859212-59-2 | Ethyl 3-iodo-4-methylbenzoate
(Catalog# : 80314)
Coming soon!
864070-44-0 | Empagliflozin
(Catalog# : 52720)
Empagliflozin (BI-10773) is a potent and selective SGLT-2 inhibitor with IC50 of 3.1
863888-33-9 | Flurpiridaz-nonradiolabeled
(Catalog# : 25203)
Flurpiridaz是一种有前景的新型心脏PET成像示踪剂,是通过用氟-18放
863888-32-8 | Flurpiridaz-Precursor
(Catalog# : 25202)
现货
897109-93-2 | F7H inhibitor
(Catalog# : 20556)
F7H is a Frizzled receptor FZD7 antagonist.
821794-92-7 | Fmk
(Catalog# : 188102)
强效不可逆RSK1/2抑制剂(IC50 = 15nm)。灭活C端自激酶域活性。
864953-29-7 | Fostemsavir
(Catalog# : 1712155)
Fostemsavir,也称为BMS-663068,是一种口服,安全有效的 HIV- 1附着抑
864731-61-3 | Fluralaner
(Catalog# : 178309)
Fluralaner也称为AH252723,是一种经口服给药的系统杀虫剂和杀螨剂。
872365-14-5 | Fevipiprant ( NVP-QAW039 )
(Catalog# : 90102)
Fevipiprant (QAW039; NVP-QAW039) is a selective, potent, reversible competitive CRTh2
885060-09-3 | Filanesib
(Catalog# : 16071102)
Filanesib, also known as ARRY-520, is a synthetic, small molecule targeting the kines
808118-40-3 | FG-4592
(Catalog# : 121407)
FG-4592 is an inhibitor of hypoxia inducible factor (HIF) prolyl hydroxylase currentl
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产品分类
信号通路
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
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----
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----
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----
RSV
----
SARS-CoV
----
Antibacterial
----
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----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
----
NEKs
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
----
Methionine Adenosyltransferase (MAT)
-- GPCR & G Protein
----
Histamine Receptor
----
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----
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----
Endothelin Receptor
----
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----
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----
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----
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----
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----
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----
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----
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----
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----
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----
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----
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----
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----
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----
SSTR
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
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----
TLR
----
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----
MALT
----
TDO
----
NOS
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
----
Reactive Oxygen Species(ROS)
----
SOD
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
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----
Na+/K+ ATPase
----
nAChR
----
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----
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----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolic Enzyme/Protease
----
PPAR
----
Proteasome
----
P450
----
Caspase
----
HSP
----
HIV Protease
----
PDE
----
MMP
----
Factor Xa
----
γ-secretase
----
Phospholipase
----
DPP4
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
NADPH-oxidase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
FPTase
----
RAR/RXR
----
Acetyl-CoA Carboxylase
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Glutaminase
----
Ketohexokinase(KHK)
----
Lipase
----
Lactate dehydrogenase
----
Glyoxalase (GLO)
----
E1/E2/E3 Enzyme
----
PANK(pantothenate kinase)
----
Phosphoglycerate Dehydrogenase (PHGDH)
----
Hemoglobin
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
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----
CGRP-Receptor
----
TRP-Channel
-- NF-κB
----
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----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
----
Vps34
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
----
Notch
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
-- Nuclear Receptor
----
Androgen Receptor(AR)
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
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--
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--
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--
Chiral Compounds
--
Deuterated
--
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--
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Nitro Compounds
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On Sale
新产品
天然化合物
最新产品
2765593-43-7 | Linafexor (别名: CS-0159)
(Catalog# : 26A089)
Linafexor(同义词:CS-0159)是法尼醇X受体(FXR)的强效非胆汁酸激
2569008-99-5 | Prifetrastat (Synonyms: PF-07248144)
(Catalog# : 26A088)
Prifetrastat (Synonyms: PF-07248144) 是一款首创、选择性、口服活性的
2417489-10-0 | Camonsertib
(Catalog# : 24052)
Camonsertib,也称为RP 3500,是一种新型、强效和选择性的ATR抑制剂,
1429882-07-4 | MRX-2843
(Catalog# : 26A087)
MRX-2843 是一种口服可用的双受体酪氨酸激酶(RTKs)抑制剂,作用
1637394-01-4 | GDC-0134
(Catalog# : 20432)
GDC-0134是一种MAP3K12(DLK)抑制剂。
2128698-24-6 | BI-847325
(Catalog# : 25046)
BI-847325是一种新型的、可口服的、竞争ATP结合位点的Aurora激酶和M
3137699-54-5 | GDD-261
(Catalog# : 26A084)
GDD-261是一种口服活性的磷酸甘油酸脱氢酶变构抑制剂(IC50=61nM)
2669009-92-9 | Atebimetinib
(Catalog# : 25148)
Atebimetinib(IMM-1-104)是一种口服的小分子MEK1和MEK2激酶变构抑制剂
3062177-59-4 | BH-30643
(Catalog# : 26A047)
BH-30643是一种新型、口服、非共价、大环、突变选择性OMNI-EGFR抑制
2490431-16-6 | ERAS-801 ( JGK-068S )
(Catalog# : 20635)
ERAS-801 ( JGK-068S ) 是一种有效的 EGFR 抑制剂。