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Cas号索引 8

• 871357-89-0 | Cenisertib (Catalog# : 010814, Cenisertib)Cenisertib is an orally bioavailable, synthetic, small-molecule multi-Aurora kinase inhibitor with potential antineoplastic activity. It selectively binds to and inhibits multipl
• 80433-71-2 | Calcium levofolinate (Catalog# : 120802, Calcium levofolinate)Coming soon!
• 849550-05-6 | Cevipabulin (Catalog# : 101206, Cevipabulin)Cevipabulin is a novel, potent, synthetic small molecule, inhibits binding of vinblastine at the Vinca alkaloid site of the _alpha__beta_-tubulin heterodimer.
• 881189-65-7 | 3-(4-Chloro-3-fluorophenyl)propionic acid (Catalog# : 90619, 3-(4-Chloro-3-fluorophenyl)propionic acid)Coming soon!
• 849217-68-1 | Cabozantinib (Catalog# : 52777, Cabozantinib)Cabozantinib (XL184, BMS-907351) is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM,
• 842133-18-0 | Canagliflozin (Catalog# : 52724, Canagliflozin)Canagliflozin(JNJ 28431754; TA 7284) is a highly potent and selective SGLT2 inhibitor for hSGLT2 with IC50 of 2.2 nM, exhibits 413-fold selectivity over hSGLT1
• 885499-61-6 | CCT128930 (Catalog# : 52635, CCT128930)CCT128930 is a novel potent ATP-competitive, selective Akt2 inhibitor with an IC50 of 6 nM; >28-fold selectivity for Akt2 than the closely related PKA kinase.
• 868540-17-4 | Carfilzomib (Catalog# : 52608, Carfilzomib)Carfilzomib (PR-171) is an irreversible proteasome inhibitor with IC50 of <5 nM.
• 83373-60-8 | D-609 (Catalog# : 19371, D-609)D-609，又称D-609 free，是一种潜在的用于胰腺癌治疗的磷脂酶C抑制剂。
• 872363-17-2 | Dipraglurant (Catalog# : 187131, Dipraglurant)Dipraglurant，也被称为ADX-48621，是mGlu5受体的负变构调制器，该受体正处于Addex疗法的开发中，用于治疗帕金森病左旋多巴诱导的运动障碍(PD-LID)。
• 827318-97-8 | 达鲁舍替 (Catalog# : 1781107, Danusertib)达鲁舍替，也称为PHA-739358，是一种小分子3 -氨基吡唑衍生物，具有潜在的抗肿瘤活性。
• 863774-58-7 | Dimethylenastron (Catalog# : 16122932, Dimethylenastron)Dimethylenastron is an inhibitor of mitotic motor kinesin Eg5 (IC50 = 200 nM). Dimethylenastron suppresses human pancreatic cancer cell migration and invasion in vitro via allost
• 850876-88-9 | Danoprevir (Catalog# : 16070107, Danoprevir)Danoprevir, also known as ITMN-191 and RG-7227, is under development by InterMune Inc and Roche Holding AG, is a promising, potent NS3/4A protease inhibitor for the oral treatmen
• 852329-66-9 | Dutogliptin (Catalog# : 011113, Dutogliptin)Dutogliptin is a potent, water soluble, selective and orally bioavailable, boronic acid-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity.
• 847499-27-8 | Delanzomib (Catalog# : 111302, Delanzomib)Delanzomib is a novel orally-active inhibitor of the chymotrypsin-like activity of the proteasome that down-modulates the nuclear factor-kappaB (NF-kappaB) activity.
• 862574-88-7 | 1-(2,2-Difluorobenzo[1,3]dioxol-5-yl)-cyclopropanecarboxylic acid (Catalog# : 92211, 1-(2,2-Difluorobenzo[1,3]dioxol-5-yl)-cyclopropanecarboxylic acid)Coming soon!
• 84315-24-2 | 3-(3,5-Difluorophenyl)propionic acid (Catalog# : 90616, 3-(3,5-Difluorophenyl)propionic acid)Coming soon!
• 89180-50-7 | 5,6-Dichloropyridazin-4-amine (Catalog# : 81006, 5,6-Dichloropyridazin-4-amine)Coming soon!
• 866405-64-3 | Dorsomorphin (Catalog# : 52744, Dorsomorphin)Dorsomorphin(Compound C; BML-275) has been shown to act as a potent and selective inhibitor of AMPK (AMP-activated protein kinase; Ki = 109 nM), induced by AICAR and metformin; a
• 89464-63-1 | DMOG (Catalog# : 52236, DMOG)Dimethyloxallyl Glycine(DMOG) is a cell permeable, competitive inhibitor of HIF-PH(HIF-1 prolyl hydroxylase).
• 870843-42-8 | E2012 (Catalog# : 1810231, E2012 )E2012是γ-secretase分泌酶调制器(GSM)。
• 848193-68-0 | EX-527 S-enantiomer (Catalog# : 17011802, EX-527 S-enantiomer)EX-527 S-enantiomer是一种有效的选择性SIRT1抑制剂，IC50为123 nM;没有对SIRT3的抑制。
• 848193-69-1 | EX-527 R-enantiomer (Catalog# : 17011801, EX-527 R-enantiomer)EX-527 R-enantiomer是对活性形式EX-527 S-enantiomer(推测为参考)的负控制。
• 828934-41-4 | Etomoxir钠盐 (Catalog# : 17011103, Etomoxir (Na salt))Etomoxir是一种在线粒体内膜的外表面的一种不可逆转的CPT-1抑制剂。
• 858668-07-2 | EMD534085 (Catalog# : 16122938, EMD534085)EMD534085 is a kinesin inhibitor currently in clinical development.
• 864821-90-9 | Eluxadoline (Catalog# : 012005, Eluxadoline)Eluxadoline is an orally active mixed opioid receptor (OR) agonist opioid receptor (OR) antagonist.
• 834153-87-6 | Elagolix (Catalog# : 121413, Elagolix)Elagolix is a Gonadotropin-Releasing Hormone (GnRH) Antagonist.
• 866588-11-6 | Ethyl 3-(4-fluorophenyl)-1H-pyrazole-5-carboxylate (Catalog# : 91707, Ethyl 3-(4-fluorophenyl)-1H-pyrazole-5-carboxylate)Coming soon!
• 859212-59-2 | Ethyl 3-iodo-4-methylbenzoate (Catalog# : 80314, Ethyl 3-iodo-4-methylbenzoate)Coming soon!
• 864070-44-0 | Empagliflozin (Catalog# : 52720, Empagliflozin)Empagliflozin (BI-10773) is a potent and selective SGLT-2 inhibitor with IC50 of 3.1 nM, exhibits >300-fold selectivity over SGLT-1, 4, 5 and 6.