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首页
抑制剂/受体激动剂
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Anti-infection
Apoptosis
Autophagy
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DNA Damage
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MAPK
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Cas号索引 2
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Cas号索引 2
25606-41-1 | 霜霉威盐酸盐
(Catalog# : 2017080115)
霜霉威盐酸盐是一种高效、广谱、氨基甲酸酯类杀菌剂。
257933-82-7 | 培利替尼
(Catalog# : 17022702)
培利替尼(EKB-569; WAY-EKB 569)是一种有效且不可逆转的IC50为38.5 nM的E
202350-68-3 | PNU-159682
(Catalog# : 16071409)
PNU-159682 is a major active metabolite of nemorubicin (MMDX) in human liver microsom
269718-84-5 | Pardoprunox
(Catalog# : 122523)
Pardoprunox is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT
219580-11-7 | PD173074
(Catalog# : 122212)
PD173074 is a small-molecule FGFR3-selective tyrosine kinase inhibitor (TKI), as a th
269718-83-4 | Pardoprunox hydrochloride
(Catalog# : 111010)
Pardoprunox hydrochloride is a novel partial dopamine D2 and D3 receptor agonist and
20062-91-3 | 3-(4-phenoxyphenyl)propanoic acid
(Catalog# : 90709)
Coming soon!
212844-53-6 | Purvalanol A
(Catalog# : 52564)
Purvalanol A(NG-60) is a potent, cell-permeable, and selective inhibitor of cyclin-de
212844-54-7 | Purvalanol B
(Catalog# : 52559)
Purvalanol B(NG-95) is a cyclin-dependent kinase inhibitor with IC50 values of 6, 6,
2645-32-1 | PR-619
(Catalog# : 52227)
PR-619 is a broad-range DUB inhibitor with potential for further development as a che
2301974-60-5 | Ranosidenib
(Catalog# : 25150)
Ranosidenib,也称为HMPL-306,是一种异柠檬酸脱氢酶(IDH)抑制剂。
2169919-21-3 | Revumenib
(Catalog# : 25140)
Revumenib, also known as SNDX-5613, is a potent and specific Menin-MLL inhibitor. It
206885-38-3 | Ronopterin
(Catalog# : 25084)
Ronopterin is a potent Nitric oxide synthase inhibitor and Neuroprotectant.
2765081-21-6 | RMC-6236
(Catalog# : 25074)
Daraxonrasib, also known as RMC-6236 and RAS-IN-2, is a potent and selective RAS(ON)
266359-83-5 | Reparixin
(Catalog# : 25050)
Reparixin is an inhibitor of CXCR2 function, which attenuates inflammatory responses
2794934-49-7 | RGT-018
(Catalog# : 24148)
RGT-018 is a potent and orally active SOS1 inhibitor with anti-tumor effects.
2204289-53-0 | (Rac)-SHIN2
(Catalog# : 24136)
(Rac)-SHIN2 is a serine hydroxymethyltransferase (SHMT) inhibitor having 1,4-dihydrop
2642037-07-6 | RMC-4998
(Catalog# : 20666)
RMC-4998 is a tri-complex inhibitor and KRASG12C inhibitor. RMC-4998 targets the acti
2503036-46-0 | RNK-05047
(Catalog# : 24008)
RNK-05047 为BRD4降解剂,其在小鼠荷瘤异种移植模型中展现出显著抑
2750709-91-0 | Resigratinib
(Catalog# : 20627)
Resigratinib is a fibroblast growth factor receptor tyrosine kinase inhibitor and ant
2031185-00-7 | Risvodetinib
(Catalog# : 20621)
Risvodetinib, also known as IkT-148009., is a brain-penetrant c-Abl inhibitor with a
2366152-15-8 | RPT193
(Catalog# : 20526)
2192215-81-7 | Ritlecitinib tosylate
(Catalog# : 20452)
Ritlecitinib, also known as PF-06651600, is a potent and selective JAK3 inhibitor. PF
2171386-10-8 | RK-287107
(Catalog# : 2071520)
RK-287107 is a potent TNKS/TNKS2 inhibitor (IC50 = 14.4 nM) with >7000-fold select
2381037-82-5 | RBN-2397
(Catalog# : 207101)
2161337-98-8 | (2R,6S)-tert-butyl 4-(4-aminobenzoyl)-2,6-dimethylpiperazine-1-carboxylate
(Catalog# : 2062334)
243984-11-4 | Resatorvid
(Catalog# : 206102)
Resatorvid, also known as TAK-242, is a cell-permeable inhibitor of TLR4 signaling, b
2262452-06-0 | RU320521
(Catalog# : 204503)
RU320521, also known as RU521; RU.521 is a potent and selective inhibitor of cGAS, in
2086689-88-3 | (2R)-2-乙炔-2-甲基-1-吡咯烷乙酸 1,1-二甲基乙酯
(Catalog# : 580586)
(2R)-2-乙炔-2-甲基-1-吡咯烷乙酸 1,1-二甲基乙酯 是 Pamiparib合成中一
2072057-17-9 | RG7834
(Catalog# : 19355)
RG7834,也称为RO7020322,是一种新型口服HBV病毒基因表达抑制剂阻断病
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产品分类
信号通路
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
抑制剂/受体激动剂
中间体
分子砌块
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Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
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--
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--
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--
On Sale
新产品
天然化合物
最新产品
2377000-84-3 | Dencatistat (STP938)
(Catalog# : 25177)
Dencatistat 是一种口服生物可利用的小分子胞苷三磷酸合酶 1 (CTPS1)
1898207-64-1 | DS-1001b
(Catalog# : 25178)
DS-1001 是一种口服的脑渗透性突变 IDH1 选择性抑制剂。
1016340-64-9 | Z57346765
(Catalog# : 25191)
Z57346765 是一种 PGK1 特异性抑制剂,可降低 PGK1 糖酵解中代谢酶的
2416095-06-0 | CBR-470-1
(Catalog# : 25192)
CBR-470-1 是诱导 Nrf2 活性的糖酵解酶 PGK1 的抑制剂。
1898206-17-1 | Safusidenib
(Catalog# : 25149)
Safusidenib,也称为DS-1001,是一种口服异柠檬酸脱氢酶[NADP]细胞质(
2803470-63-3 | HC-7366
(Catalog# : 25076)
HC-7366 is a potent and selective activator of the general control nonderepressible 2
146426-40-6 | Flavopiridol ( 夫拉平度 )
(Catalog# : 237071)
Alvocidib is a synthetic dihydroxyflavone that is 5,7-dihydroxyflavone which is subst
2201056-66-6 | AG-270
(Catalog# : 25176)
MAT2A 抑制剂 AG-270 是一种口服的蛋氨酸腺苷转移酶 II α (MAT2A) 小分
618913-30-7 | AZD-5904
(Catalog# : 181121)
AZD5904是一个有效的口服生物利用率MPO抑制剂。在临床前研究中,AZ
2035010-37-6 | ALT-007
(Catalog# : 25157)
ALT-007 是一种口服生物可利用的 SPT 抑制剂,比多球菌素更有效,