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Amines
Amino Acids
Anilines
Boronic Acids
Bromides
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Deuterated
Fluorides
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
Microbiology
Others
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
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联系我们
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Cas号索引 1
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Cas号索引 1
1434048-34-6 | GDC-0853
(Catalog# : 16123004)
GDC-0853 is orally available inhibitor of Bruton's tyrosine kinase (BTK) with potenti
1095173-27-5 | Glasdegib (PF-04449913)
(Catalog# : 16122787)
Glasdegib (PF-04449913) is a potent, and orally bioavailable Smoothened (Smo) inhibit
136194-77-9 | Go6976
(Catalog# : 16122723)
Go6976 is a potent PKC inhibitor with IC50 of 7.9 nM, 2.3 nM, and 6.2 nM for PKC (Rat
1254036-66-2 | GSK2292767
(Catalog# : 16122702)
GSK2292767 is a potent and selective PI3K inhibitor.GSK2292767 is highly selective fo
1474110-21-8 | GSK2981278
(Catalog# : 6111521)
ROR modulator 1 is a retinoid-related orphan receptor gamma (RORy) modulator, extract
1616391-87-7 | GSK-591
(Catalog# : 6111009)
EPZ015866 (GSK591) is a potent selective inhibitor of the arginine methyltransferase
1254036-71-9 | GSK2269557 free base
(Catalog# : 611826)
GSK-2269557 (free base) is a potent and selective PI3Kδ inhibitor over the closely r
1047635-80-2 | GSK2141795 (hydrochloride)
(Catalog# : 611807)
GSK2141795 Hcl is a potent and selective pan-Akt inhibitor with IC50 values of 180 nM
1432913-36-4 | GX-674
(Catalog# : 1681201)
GX-674 is an aryl sulfonamide class of antagonists that inhibits Nav1.7.Nav (voltage-
1382979-44-3 | GDC-0084
(Catalog# : 16071405)
GDC-0084, also known as RG7666, is a phosphatidylinositol 3-kinase (PI3K) inhibitor w
1254053-43-4 | Gilteritinib
(Catalog# : 16071108)
Gilteritinib, also known as (ASP2215, is a potent FLT3/AXL inhibitor, which showed po
186452-09-5 | GPI-1046
(Catalog# : 16071027)
GPI-1046
1346607-05-3 | GSK621
(Catalog# : 16070905)
GSK621 is a specific and potentAMPKactivator.
1300031-49-5 | GSK1210151A
(Catalog# : 16070808)
GSK1210151A, also known as I-BET151, is a BET bromodomain inhibitor, which blocks rec
1453848-26-4 | GDC-0994
(Catalog# : 16062801)
GDC-0994, also known as RG7842, is an orally available inhibitor of extracellular sig
117928-94-6 | GLYX 13
(Catalog# : 011809)
Coming soon!
1168091-68-6 | GDC-0623
(Catalog# : 010811)
GDC-0623 is a potent, ATP-uncompetitive inhibitors of MEK1(Ki=0.13 nM, +ATP); 6-fold
1075236-89-3 | Gepotidacin
(Catalog# : 010610)
Gepotidacin is a potent Type II DNA topoisomerase inhibitor. Gepotidacin is a novel a
1217457-86-7 | GGTI-298
(Catalog# : 010609)
GGTI-298 is a potent geranylgeranyltransferase-I (GGTase-I) inhibitor with potential
1443461-21-9 | GSK2838232
(Catalog# : 122924)
GSK2838232 is a novel human immune virus (HIV) maturation inhibitor being developed f
1431368-48-7 | GSK-LSD1 2HCl
(Catalog# : 122505)
Coming soon!
1346704-33-3 | GSK343
(Catalog# : 122402)
GSK343 is a potent and selective EZH2 inhibitor with IC50 of 4 nM, showing 60 fold se
1032823-75-8 | GSK1292263
(Catalog# : 121430)
GSK1292263 is a novel GPR119 receptor agonist used for the treatment of type 2 diabet
1089283-49-7 | GSK1904529A
(Catalog# : 121428)
GSK1904529A is a selective inhibitor of IGF-1R and IR with IC50 of 27 nM and 25 nM, &
1229236-86-5 | Gandotinib(LY2784544)
(Catalog# : 91415)
Gandotinib is an orally bioavailable imidazopyridazine and inhibitor of Janus kinase
1365888-06-7 | GDC-0810 ( Brilanestrant , ARN-810 )
(Catalog# : 90731)
GDC-0810 (Brilanestrant, ARN-810, RG6046) is a selective estrogen receptor degrader (
1380672-07-0 | G007-LK
(Catalog# : 62908)
G007-LK is specific tankyrase 1/2 inhibitor.G007-LK (66) displayed high selectivity t
1207360-89-1 | GDC-0349
(Catalog# : 62702)
GDC-0349 is a potent and selective ATP-competitive inhibitor of mTOR.
103766-25-2 | Gimeracil
(Catalog# : 52804)
Gimeracil(Gimestat) is an inhibitor of dihydropyrimidine dehydrogenase (DPYD), which
1260907-17-2 | GSK 525762A
(Catalog# : 52745)
GSK 525762A (I-BET 762) is an inhibitor for BET proteins with IC50 of ~35 nM.
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产品分类
信号通路
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
2377000-84-3 | Dencatistat (STP938)
(Catalog# : 25177)
Dencatistat 是一种口服生物可利用的小分子胞苷三磷酸合酶 1 (CTPS1)
1898207-64-1 | DS-1001b
(Catalog# : 25178)
DS-1001 是一种口服的脑渗透性突变 IDH1 选择性抑制剂。
1016340-64-9 | Z57346765
(Catalog# : 25191)
Z57346765 是一种 PGK1 特异性抑制剂,可降低 PGK1 糖酵解中代谢酶的
2416095-06-0 | CBR-470-1
(Catalog# : 25192)
CBR-470-1 是诱导 Nrf2 活性的糖酵解酶 PGK1 的抑制剂。
1898206-17-1 | Safusidenib
(Catalog# : 25149)
Safusidenib,也称为DS-1001,是一种口服异柠檬酸脱氢酶[NADP]细胞质(
2803470-63-3 | HC-7366
(Catalog# : 25076)
HC-7366 is a potent and selective activator of the general control nonderepressible 2
146426-40-6 | Flavopiridol ( 夫拉平度 )
(Catalog# : 237071)
Alvocidib is a synthetic dihydroxyflavone that is 5,7-dihydroxyflavone which is subst
2201056-66-6 | AG-270
(Catalog# : 25176)
MAT2A 抑制剂 AG-270 是一种口服的蛋氨酸腺苷转移酶 II α (MAT2A) 小分
618913-30-7 | AZD-5904
(Catalog# : 181121)
AZD5904是一个有效的口服生物利用率MPO抑制剂。在临床前研究中,AZ
2035010-37-6 | ALT-007
(Catalog# : 25157)
ALT-007 是一种口服生物可利用的 SPT 抑制剂,比多球菌素更有效,