GSK2636771
编号: 52618
Cas号: 1372540-25-4
纯度: 98% by HPLC
GSK2636771 is a potent, orally bioavailable and selective inhibitor of PI3K (0.89 nM), with >900-fold selectivity over PI3K/PI3K and >10-fold over PI3K. It inhibits AKT phosphorylation and downstream signalling measured as decrease of PRAS40-, GSK3-, and RPS6-phosphorylation in PTEN mutant cell lines.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | GSK2636771 |
|---|---|
| Iupac 化学名称 | 2-methyl-1-(2-methyl-3-(trifluoromethyl)benzyl)-6-morpholino-1H-benzo[d]imidazole-4-carboxylic acid |
| 同义词 | GSK-2636771,GSK 2636771 |
| 英文同义词 | GSK-2636771,GSK 2636771 |
| 分子式 | C22H22F3N3O3 |
| 分子量 | 433.42 |
| Smile | CC1=NC2=C(N1CC1=C(C(=CC=C1)C(F)(F)F)C)C=C(C=C2C(=O)O)N2CCOCC2 |
| InChiKey | XTKLTGBKIDQGQL-UHFFFAOYSA-N |
| InChi | InChI=1S/C22H22F3N3O3/c1-13-15(4-3-5-18(13)22(23,24)25)12-28-14(2)26-20-17(21(29)30)10-16(11-19(20)28)27-6-8-31-9-7-27/h3-5,10-11H,6-9,12H2,1-2H3,(H,29,30) |
| Cas号 | 1372540-25-4 |
| 相关CAS号 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
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| 大货 | 询价 | 询价 | 询价 |
