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+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
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Deuterated
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Peg Linkers
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Pyrimidines
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Cas号索引 1
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Cas号索引 1
1618658-88-0 | CC-671
(Catalog# : L20343)
CC-671 is a potent and selective dual inhibitor of TTK (Mps1) and CLK2.
1258296-60-4 | RO495
(Catalog# : L20340)
RO495 (CS-2667) is a potent inhibitor of Non-receptor tyrosine-protein kinase 2 (TYK2
1038984-34-7 | 3-cyclopropyl-7-methyl-6-nitro-2H-benzo[e][1,3]oxazin-4(3H)-one
(Catalog# : 20328)
1262414-04-9 | Cenerimod ( ACT-334441 )
(Catalog# : 20313)
Cenerimod 是一种有效的、具有口服活性免疫调节剂,EC50 值为 2.7 nM
16499-64-2 | 4-氯-6-三氟甲基喹唑啉
(Catalog# : 20310)
1979939-16-6 | CRT0273750
(Catalog# : 20258)
CRT0273750 modulates LPA levels in plasma and is suitable for in vivo studies.
1628265-17-7 | 2-氯-4-(4-氟苯基)-5-噻唑甲腈
(Catalog# : 2091202)
1279680-68-0 | CL2A-SN38 DCA
(Catalog# : 2071556)
CL2A-SN38 is a SN38 derivative with a peptide-linker which can easily react with anti
1846570-31-7 | CM-272
(Catalog# : 2071538)
CM-272 is a first-in-class reversible dual small molecule inhibitor against G9a and D
189746-21-2 | 5-chloro-2,6-dimethoxy-4-methyl-8-nitroquinoline
(Catalog# : 2062026)
1246964-32-8 | CLEFMA
(Catalog# : 615201)
CLEFMA has anti-proliferative activity in H441 cells. CLEFMA may induce autophagic ce
145915-58-8 | CGP52411
(Catalog# : 2061306)
CGP52411, also known as DAPH, is a selective inhibitor of the epidermal growth factor
199735-88-1 | CADD522
(Catalog# : 2051505)
CADD522 is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA bind
1010100-07-8 | CC-885
(Catalog# : 2041501)
CC-885 is a potent Cereblon Modulator with potent antitumor activity mediated through
1860875-51-9 | CC-90009
(Catalog# : 203071)
CC-90009 是一种 cereblon (CRBN) E3 连接酶调节剂。CC-90009 与 CRBN 特异性
189746-19-8 | 5-氯-2,6-二甲氧基-4-甲基喹啉
(Catalog# : 4281903)
5-氯-2,6-二甲氧基-4-甲基喹啉是一个他非诺喹原料药合成中非常关
1181083-81-7 | CLP-290
(Catalog# : 193286)
CLP-290是一种新型的KCC2调制器和CLP-257的前药,对KCC2相关的Cl-转运
1802632-22-9 | CT-1812
(Catalog# : 193283)
CT-1812是一类口服的sigma-2/PGRMC1拮抗剂(α-β-低聚物受体拮抗剂),目
1384860-29-0 | Conteltinib
(Catalog# : 19342)
Conteltinib是一种酪氨酸激酶抑制剂和抗肿瘤药。
1358099-18-9 | C25-140
(Catalog# : 192274)
C25-140是环-E3连接酶(TRAF6) / E2酶(Ubc13)结合的一级蛋白-蛋白相互作用
1095382-05-0 | CCT-137690
(Catalog# : 192192)
CCT137690是一种极光激酶抑制剂CCT137690,是一种高选择性的口服生物
1418274-28-8 | Cilofexor ( GS-9674 )
(Catalog# : 19132)
Cilofexor(也称为 GS-9674)是一种非甾体法尼醇 X 受体(FXR)激动剂
1402709-93-6 | CCT241736
(Catalog# : 1812283)
CCT241736是一种有效且具有口服活性的日常FLT3-Aurora抑制剂。
1801343-74-7 | CA-4948
(Catalog# : 1811292)
CA-4948是一种生物活性化学物。
192322-50-2 | CGP-71683A盐酸盐
(Catalog# : 18792)
CGP 71683A是一种有效且高选择性的NPY Y(5)受体的非肽拮抗剂,在肥胖
1437321-24-8 | CEP-40783
(Catalog# : 186281)
CEP-40783,又称RXDX-106,是AXL和c-Met的一种有效、选择性和口服的抑
125316-60-1 | CD437
(Catalog# : 185316)
CD437合成维生素a是一个RARγ-selective受体激动剂。
1345810-21-0 | CB-1158
(Catalog# : 185315)
CB-1158,又称INCB01158,是一种有效的精氨酸酶抑制剂。
153259-65-5 | 西洛司特
(Catalog# : 185291)
西洛司特是一种用于治疗呼吸系统疾病,如哮喘和慢性阻塞性肺病
1276105-89-5 | CNX-1351
(Catalog# : 185174)
CNX-1351是PI3K的选择性共价抑制剂。
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产品分类
信号通路
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
85622-93-1 | Temozolomide
(Catalog# : 25209)
替莫唑胺是一种烷化剂。
2035010-37-6 | ALT-007
(Catalog# : 25157)
ALT-007 是一种口服生物可利用的 SPT 抑制剂,比多球菌素更有效,
2376397-93-0 | Opakalim
(Catalog# : 25193)
Opakalim(BHV-7000)是Kv7.2/7.3钾通道(KCNQ2/3)的口服小分子激活剂,
2102501-84-6 | PF-06835919 ( MDK-1846 )
(Catalog# : 193264)
MDK1846是一种强效的酮己糖激酶(KHK)抑制剂。
2271348-04-8 | MK256
(Catalog# : 25208)
MK256是一种新型CDK8抑制剂,通过下调STAT通路在急性髓系白血病(
2351225-46-0 | NSD1 抑制剂 BT5
(Catalog# : 25207)
BT5可有效抑制NSD1,与细胞中的SET结构域结合,并降低H3K36me2水平。
1049704-18-8 | MA242 TFA
(Catalog# : 25206)
MA242是一种MDM2和NFAT1双重抑制剂,可诱导MDM2自泛素化及降解,并抑
2800223-30-5 | Dabogratinib ( TYRA-300 )
(Catalog# : 24073)
Dabogratinib ( TYRA-300 )是一种口服选择性成纤维细胞生长因子受体3(
N/A | AF710B
(Catalog# : 25205)
AF710B 是一种高效、选择性变构 M1 毒蕈碱和 σ1 受体激动剂。 AF710
2957874-18-7 | MAT2A inhibitor 5
(Catalog# : 25204)
MAT2A抑制剂5具有抑制MAT2A的高效力和对MTAP缺失的癌症细胞系的显著