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抑制剂/受体激动剂
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Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
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Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
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Neuronal Signaling
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Metabolism
Anti-infection
Proteases
Immunology & Inflammation
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others
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
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+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
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定制合成
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订购信息
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公司简介
联系我们
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Cas号索引 1
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Cas号索引 1
1173900-33-8 | AZD6482
(Catalog# : 51603)
AZD6482 is aPI3Kinhibitor withIC50of 10 nM, 8-, 87- and 109-fold more selective to PI
1204144-28-4 | AZD1208
(Catalog# : 51702)
AZD1208 is a potent, highly selective, and orally available Pim kinase inhibitor that
1124329-14-1 | AZ3146
(Catalog# : 51903)
AZ3146 is a selectiveMps1inhibitor withIC50of ~35 nM, contributes to recruitment of C
1056901-62-2 | AT13148
(Catalog# : 51902)
AT13148, a first-in-class multi-AGC kinase inhibitor, against gastric cancer cells. A
1990504-34-1 | Bomedemstat
(Catalog# : 24001)
Bomedemstat 是一种口服的、不可逆的赖氨酸特异性去甲基酶 1 (LSD1)
1809010-52-3 | Berotralstat HCl
(Catalog# : 20619)
Berotralstat HCl is a novel selective inhibitor of plasma kallikrein, blocking the en
1672668-24-4 | Belzutifan
(Catalog# : 20606)
Belzutifan, also known as PT2977 and MK-6482, is HIF-2alpha inhibitor. PT2977 binds t
1478364-68-9 | BI-1467335 HCl
(Catalog# : 20601)
BI-1467335, also known as PXS-4728A, is a SSAO/VAP inhibitor potentially for the trea
1440964-89-5 | Bozitinib
(Catalog# : 20599)
Bozitinib is a highly selective c-MET kinase inhibitor with blood-brain barrier perme
1815613-42-3 | BMS-986176
(Catalog# : 20597)
BMS-986176, also known as LX9211, is a highly selective, CNS penetrant, potent AAK1 i
120533-76-8 | BML-278
(Catalog# : 20554)
BML-278 is an activator of sirtuin 1 (SIRT1) that has an EC150 value (effective conce
1478712-37-6 | BMS-986120
(Catalog# : 20519)
BMS-986120 is a potent and selective oral antagonist of protease-activated receptor-4
1478711-48-6 | BMS-986141
(Catalog# : 20518)
BMS-986141 is an Orally-Active Small-Molecule Antagonist of the Platelet Protease-Act
1423719-30-5 | BI 1015550 ( Nerandomilast )
(Catalog# : 230402)
BI 1015550 ( Nerandomilast ) 是一种口服磷酸二酯酶 4B (PDE4B) 优先抑制剂
1883299-62-4 | Brepocitinib ( PF-06700841 )
(Catalog# : 232251)
Brepocitinib 是一种潜在的 TYK2 和 JAK1双重选择性抑制剂,IC50 分别为
1798787-27-5 | BIIB068
(Catalog# : 20453)
1428652-17-8 | Baxdrostat
(Catalog# : 20451)
Baxdrostat is an aldosterone synthase inhibitor.
1912445 -55-6 | BMS-986195
(Catalog# : 20444)
1912445-55-6 | Branebrutinib
(Catalog# : 20428)
Branebrutinib, also known as BMS-986195, is a potent, covalent, irreversible inhibito
1060810-24-3 | 1-(4-溴-6-甲基吡啶-2-基)乙-1-酮
(Catalog# : 171454)
1-(4-溴-6-甲基吡啶-2-基)乙-1-酮, CAS 1060810-24-3.
195615-84-0 | Blarcamesine HCl
(Catalog# : 6111905)
Anavex2-73 is a muscarinic/σ1 ligand. ANAVEX2-73 (0.01-3.0 mg/kg i.p.) alleviated th
1055-55-6 | Bunamidine hydrochloride
(Catalog# : 20271)
Bunamidine is a anti-parasitic drug, which was approved by FDA for the treatment of t
1303515-32-3 | BI-187004
(Catalog# : 21224)
BI-187004, also known as VTP-34072, is an 11β-hydroxysteroid dehydrogenase 1 inhibit
1207853-23-3 | (2S,5R)-5-氨基-2-甲基哌啶-1-甲酸苄酯盐酸盐
(Catalog# : 20103006)
1333714-43-4 | Benpyrine racemate
(Catalog# : 2091907)
(Rac)-Benpyrine is a racemate of Benpyrine. (Rac)-Benpyrine is a potent and orally ac
1660117-38-3 | BI-894999
(Catalog# : 2091902)
BI-894999 is a potent and selective BET inhibitor potentially useful for the Treatmen
1628264-07-2 | 6-BROMO-2-ETHYL-N,8-DIMETHYLIMIDAZO[1,2-A]PYRIDIN-3-AMINE
(Catalog# : 2091201)
1818314-88-3 | BMS-1166
(Catalog# : 2073102)
BMS-1166是一种有效的PD-1 / PD-L1相互作用抑制剂,IC50为1.4 nM,可拮抗
1891087-61-8 | BAY-1816032
(Catalog# : 2071615)
BAY-1816032 is a potent and oral available BUB1 (budding uninhibited by benzimidazole
1301708-12-2 | BMVC-8C3O
(Catalog# : 2071550)
BMVC-8C3O is a DNA G-quadruplexe (G4) ligand which can induce topological conversion
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
1393466-87-9 | PLX8394
(Catalog# : 20613)
PLX8394 is an orally bioavailable inhibitor of serine/threonine-protein kinase B-raf
2365193-22-0 | Zelasudil
(Catalog# : 24014)
Zelasudil 是一种有效的、高选择性的口服活性抑制剂,针对 Rho 相关
2134675-36-6 | Ziftomenib ( KO-539 )
(Catalog# : 24013)
Ziftomenib 是一种口服、有效、选择性的小分子抑制剂,针对 menin 和
1640282-42-3 | Zunsemetinib
(Catalog# : 24012)
Zunsemetinib是一种在研口服丝裂原活化蛋白激酶活化蛋白激酶2(MK2
2728667-27-2 | Zongertinib ( BI 1810631 )
(Catalog# : 24011)
Zongertinib [BI 1810631] 是一种人表皮生长因子受体 2 (HER2) 抑制剂。
2272904-53-5 | Zasocitinib
(Catalog# : 24010)
Zasocitinib是一种作用于非受体酪氨酸蛋白激酶 (TYK2)靶点的抑制
2503036-46-0 | RNK-05047
(Catalog# : 24008)
RNK-05047 为BRD4降解剂,其在小鼠荷瘤异种移植模型中展现出显著抑
1001288-58-9 | Asengeprast (FT011)
(Catalog# : 24009)
Asengeprast (FT011) 是一种抗纤维化剂,降低胶原蛋白 I 和 III 的 mRNA
2490431-16-6 | ERAS-801 ( JGK-068S )
(Catalog# : 20635)
ERAS-801 ( JGK-068S ) 是一种有效的 EGFR 抑制剂。
209746-59-8 | T-1095
(Catalog# : 24004)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).