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抑制剂/受体激动剂
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
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MAPK
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Cas号索引 1
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Cas号索引 1
153436-53-4 | AG-1478
(Catalog# : 52222)
AG-1478 (NSC 693255) is a selective EGFR inhibitor with IC50 of 3 nM; almost no activ
1469924-27-3 | Atglistatinc
(Catalog# : 52240)
Atglistatin is a highly potent, selective and competitive inhibitor of adipose trigly
1226895-20-0 | ATB-346
(Catalog# : 52232)
ATB-346 is a novel hydrogen sulphide-releasing derivative of naproxen with markedly r
173352-21-1 | Afobazole
(Catalog# : 52242)
Afobazole (CM346) is an anxiolytic drug; produces anxiolytic and neuroprotective effe
1256580-46-7 | Alectinib(CH5424802)
(Catalog# : 51907)
Alectinibis a second-generation, orally active, potent and highly selective inhibitor
1173900-33-8 | AZD6482
(Catalog# : 51603)
AZD6482 is aPI3Kinhibitor withIC50of 10 nM, 8-, 87- and 109-fold more selective to PI
1204144-28-4 | AZD1208
(Catalog# : 51702)
AZD1208 is a potent, highly selective, and orally available Pim kinase inhibitor that
1124329-14-1 | AZ3146
(Catalog# : 51903)
AZ3146 is a selectiveMps1inhibitor withIC50of ~35 nM, contributes to recruitment of C
1056901-62-2 | AT13148
(Catalog# : 51902)
AT13148, a first-in-class multi-AGC kinase inhibitor, against gastric cancer cells. A
1616385-51-3 | Bezuclastinib
(Catalog# : 25198)
Bezuclastinib是KIT D816V突变体以及其他KIT外显子17突变体激酶活性的口
1402608-02-9 | BAY-1125976
(Catalog# : 25048)
BAY-1125976 is a potent and selective allosteric AKT1/2 inhibitor. BAY-1125976 exhibi
1598424-76-0 | BMS-466442
(Catalog# : 25032)
BMS-466442 是 asc-1 的小分子抑制剂。
1990504-34-1 | Bomedemstat
(Catalog# : 24001)
Bomedemstat 是一种口服的、不可逆的赖氨酸特异性去甲基酶 1 (LSD1)
1809010-52-3 | Berotralstat HCl
(Catalog# : 20619)
Berotralstat HCl is a novel selective inhibitor of plasma kallikrein, blocking the en
1672668-24-4 | Belzutifan
(Catalog# : 20606)
Belzutifan, also known as PT2977 and MK-6482, is HIF-2alpha inhibitor. PT2977 binds t
1478364-68-9 | BI-1467335 HCl
(Catalog# : 20601)
BI-1467335, also known as PXS-4728A, is a SSAO/VAP inhibitor potentially for the trea
1440964-89-5 | Bozitinib
(Catalog# : 20599)
Bozitinib is a highly selective c-MET kinase inhibitor with blood-brain barrier perme
1815613-42-3 | BMS-986176
(Catalog# : 20597)
BMS-986176, also known as LX9211, is a highly selective, CNS penetrant, potent AAK1 i
120533-76-8 | BML-278
(Catalog# : 20554)
BML-278 is an activator of sirtuin 1 (SIRT1) that has an EC150 value (effective conce
1478712-37-6 | BMS-986120
(Catalog# : 20519)
BMS-986120 is a potent and selective oral antagonist of protease-activated receptor-4
1478711-48-6 | BMS-986141
(Catalog# : 20518)
BMS-986141 is an Orally-Active Small-Molecule Antagonist of the Platelet Protease-Act
1423719-30-5 | BI 1015550 ( Nerandomilast )
(Catalog# : 230402)
BI 1015550 ( Nerandomilast ) 是一种口服磷酸二酯酶 4B (PDE4B) 优先抑制剂
1883299-62-4 | Brepocitinib ( PF-06700841 )
(Catalog# : 232251)
Brepocitinib 是一种潜在的 TYK2 和 JAK1双重选择性抑制剂,IC50 分别为
1798787-27-5 | BIIB068
(Catalog# : 20453)
1428652-17-8 | Baxdrostat
(Catalog# : 20451)
Baxdrostat is an aldosterone synthase inhibitor.
1912445 -55-6 | BMS-986195
(Catalog# : 20444)
1912445-55-6 | Branebrutinib
(Catalog# : 20428)
Branebrutinib, also known as BMS-986195, is a potent, covalent, irreversible inhibito
1060810-24-3 | 1-(4-溴-6-甲基吡啶-2-基)乙-1-酮
(Catalog# : 171454)
1-(4-溴-6-甲基吡啶-2-基)乙-1-酮, CAS 1060810-24-3.
195615-84-0 | Blarcamesine HCl
(Catalog# : 6111905)
Anavex2-73 is a muscarinic/σ1 ligand. ANAVEX2-73 (0.01-3.0 mg/kg i.p.) alleviated th
1055-55-6 | Bunamidine hydrochloride
(Catalog# : 20271)
Bunamidine is a anti-parasitic drug, which was approved by FDA for the treatment of t
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产品分类
信号通路
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
----
NEKs
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
----
Methionine Adenosyltransferase (MAT)
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
----
GLP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
----
Reactive Oxygen Species(ROS)
----
SOD
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolic Enzyme/Protease
----
PPAR
----
Proteasome
----
P450
----
Caspase
----
HSP
----
HIV Protease
----
PDE
----
MMP
----
Factor Xa
----
γ-secretase
----
Phospholipase
----
DPP4
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
NADPH-oxidase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
FPTase
----
RAR/RXR
----
Acetyl-CoA Carboxylase
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Glutaminase
----
Ketohexokinase(KHK)
----
Lipase
----
Lactate dehydrogenase
----
Glyoxalase (GLO)
----
E1/E2/E3 Enzyme
----
PANK(pantothenate kinase)
----
Phosphoglycerate Dehydrogenase (PHGDH)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
----
CGRP-Receptor
----
TRP-Channel
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
----
Vps34
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
----
Notch
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
-- Nuclear Receptor
----
Androgen Receptor(AR)
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
3054692-62-2 | ECI830
(Catalog# : 26A031)
ECI830是一种实验性的CDK2抑制剂。
1394076-92-6 | GNE-317
(Catalog# : 52282)
GNE-317 is a potent, brain-penetrantPI3Kinhibitor
3118994-80-9 | DPTX-3186
(Catalog# : 26A010)
DPTX3186 是一种口服的小分子凝聚体调节剂 (c-mod),可抑制 β-catenin
435327-40-5 | Avasopasem manganese (GC-4419; M-40419)
(Catalog# : 25108)
Avasopasem manganese, 也称为GC-4419、M 40419和SC-72325A,是超氧化物歧化酶
1421936-85-7 | Iclepertin (BI-425809)
(Catalog# : 24084)
Iclepertin(BI-425809)是一种口服的GlyT-1小分子抑制剂,用于治疗与
4727-31-5 | Kartogenin ( KGN )
(Catalog# : 52215)
Kartogenin(KGN)是一种合成小分子,通过激活smad-4/5通路刺激软骨细
218791-21-0 | Imisopasem manganese ( M40403; GC4403 )
(Catalog# : 72602)
Imisopasem manganese ( M40403; GC4403 ) 是一种稳定的非肽类 MnSOD 类似物,
2311863-36-0 | Apecotrep (BI 764198)
(Catalog# : 26A048)
Apecotrep(BI 764198)是一种潜在的同类首创、口服、选择性的TRPC6抑
902614-04-4 | Pantothenate kinase-IN-2
(Catalog# : 26A038)
Pantothenate kinase-IN-2是一种泛酸激酶抑制剂,对PanK2的IC50值为92 nM,
3062177-59-4 | BH-30643
(Catalog# : 26A047)
BH-30643是一种新型、口服、非共价、大环、突变选择性OMNI-EGFR抑制