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抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
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MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
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Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
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others
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
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+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
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订购信息
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Cas号索引 1
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Cas号索引 1
1421693-22-2 | CDKI-73
(Catalog# : 611920)
CDKI-73 is a potent CDK9 inhibitor with Ki of 4 nM; shows selective toxicity to CLL c
1391855-95-0 | CDK9-IN-6
(Catalog# : 611919)
CDK9-IN-6 is a CDK9 inhibitor, refers to Example 399 in WO 2012101062 A1
1402821-24-2 | Ca2+ channel agonist 1
(Catalog# : 611918)
Ca2+ channel agonist 1 is a N-type Ca2+ channel activity agonist, with EC50 of 14.23
1309357-15-0 | CX-4945 sodium salt
(Catalog# : 611912)
CX-4945 (Silmitasertib) sodium salt is a potent and selective ATP-competitive small m
1431697-78-7 | CAL-130 Hydrochloride
(Catalog# : 611823)
CAL-130 Hcl is a novel phosphoinositide 3-kinase (PI3K) inhibitor. It is reported tha
1431697-74-3 | CAL-130
(Catalog# : 611822)
CAL-130 is a novel phosphoinositide 3-kinase (PI3K) inhibitor. It is reported that co
168425-64-7 | Compound 401
(Catalog# : 611816)
Compound 401 is a synthetic inhibitor of DNA-PK (IC50 = 0.28 M) that also targets mTO
1300118-55-1 | CC-115 hydrochloride
(Catalog# : 611815)
CC-115 hydrochloride is a inhibitor of mTOR/DNA-PK (IC50= 21/ 13 nM). CC-115 shows go
1218777-13-9 | CAY10505
(Catalog# : 160926016)
CAY10505 is a phosphatidylinositol 3-kinase- inhibitor , was found to significantly i
1007207-67-1 | CH5132799 (PA-799)
(Catalog# : 160926015)
CH5132799, also known as PA-799, is a novel class I PI3K inhibitor, which exhibited a
1489389-18-5 | CCT245737
(Catalog# : 16090101)
CCT245737(CCT-245737, CAS 1489389-18-5) is the first orally active, clinical developm
1564286-55-0 | CWHM-12
(Catalog# : 16071407)
vitro ligand-binding assays, with somewhat less potency against v5 than against the o
1032568-63-0 | Copanlisib
(Catalog# : 16070917)
Copanlisib, also known as BAY 80-6946, is a phosphoinositide 3-kinase (PI3K) inhibito
1404095-34-6 | CCT244747
(Catalog# : 16070913)
CCT244747 is a novel potent, highly selective, orally active ATP-competitive CHK1 inh
134448-10-5 | CA-074
(Catalog# : 16062115)
CA-074
163042-96-4 | CF-102
(Catalog# : 16053104)
CF-102, also known as 2-Cl-IB-MECA, is an orally bioavailable, synthetic, highly sele
156177-65-0 | CEP-1347
(Catalog# : 032402)
Coming soon!
1446144-04-2 | CPI-203
(Catalog# : 030201)
CPI 203 is a novel potent, selective and cell permeable inhibitor of the bromodomain
194423-06-8 | CL-387785
(Catalog# : 022202)
CL-387785 is an irreversible inhibitor of EGFR with IC50 of 370+/-120 pM; is able to
1228013-30-6 | CC-223
(Catalog# : 021802)
CC-223 is a potent mTOR kinase inhibitor (IC50=16 nM), with >150-fold sensitivity
1228013-15-7 | CC-115
(Catalog# : 012004)
CC-115 is a dual inhibitor of DNA-dependent protein kinase and mammalian target of ra
1542705-92-9 | CB-5083
(Catalog# : 012002)
CB-5083 is a novel first in class, potent orally bio-available p97 inhibitor that dis
1056636-06-6 | CYT387 sulfate salt
(Catalog# : 011916)
CYT387 sulfate is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM,
1051375-10-0 | Cabotegravir
(Catalog# : 011816)
Cabotegravir is a potent HIV integrase inhibitor as an oral lead-in tablet and long-a
184025-19-2 | Ciproxifan maleate
(Catalog# : 010420)
Ciproxifan maleate is a highly potent and selective histamin H3-receptor antagonist w
1338806-73-7 | CFI-400945
(Catalog# : 123012)
CFI-400945 is an orally available fumarate salt form of CFI-400945, a polo-like kinas
1339928-25-4 | CUDC-907
(Catalog# : 12309)
CUDC-907 potently inhibits class I PI3Ks as well as classes I and II HDAC enzymes.
176957-55-4 | CCT007093
(Catalog# : 122839)
CCT 007093 is an effective PPM1D inhibitor that selectively reduces viability of huma
146062-49-9 | CAY10415
(Catalog# : 122836)
CAY10415 is a novel peroxisome proliferator-activated receptor (PPAR) ligand.
1802175-06-9 | CPI-360
(Catalog# : 122816)
CPI-360 is a potent, selectiveEZH2inhibitor with IC50 of 0.5 nM and 2.5 nM nM for wt
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
1393466-87-9 | PLX8394
(Catalog# : 20613)
PLX8394 is an orally bioavailable inhibitor of serine/threonine-protein kinase B-raf
2365193-22-0 | Zelasudil
(Catalog# : 24014)
Zelasudil 是一种有效的、高选择性的口服活性抑制剂,针对 Rho 相关
2134675-36-6 | Ziftomenib ( KO-539 )
(Catalog# : 24013)
Ziftomenib 是一种口服、有效、选择性的小分子抑制剂,针对 menin 和
1640282-42-3 | Zunsemetinib
(Catalog# : 24012)
Zunsemetinib是一种在研口服丝裂原活化蛋白激酶活化蛋白激酶2(MK2
2728667-27-2 | Zongertinib ( BI 1810631 )
(Catalog# : 24011)
Zongertinib [BI 1810631] 是一种人表皮生长因子受体 2 (HER2) 抑制剂。
2272904-53-5 | Zasocitinib
(Catalog# : 24010)
Zasocitinib是一种作用于非受体酪氨酸蛋白激酶 (TYK2)靶点的抑制
2503036-46-0 | RNK-05047
(Catalog# : 24008)
RNK-05047 为BRD4降解剂,其在小鼠荷瘤异种移植模型中展现出显著抑
1001288-58-9 | Asengeprast (FT011)
(Catalog# : 24009)
Asengeprast (FT011) 是一种抗纤维化剂,降低胶原蛋白 I 和 III 的 mRNA
2490431-16-6 | ERAS-801 ( JGK-068S )
(Catalog# : 20635)
ERAS-801 ( JGK-068S ) 是一种有效的 EGFR 抑制剂。
209746-59-8 | T-1095
(Catalog# : 24004)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).