Cenerimod ( ACT-334441 )
编号: 20313
Cas号: 1262414-04-9
纯度: ≧98.0%
Cenerimod is a potent and orally active immunomodulator, exhibited EC50 value of 2.7 nM. Cenerimod is an agonist for the G protein-coupled receptor S1 P1/EDG1 and has a powerful and long-lasting immunomodulating effect which is achieved by reducing the number of circulating and infiltrating T- and B-lymphocytes, without affecting their maturation, memory, or expansion. Cenerimod may be useful for prevention or treatment of diseases associated with an activated immune system.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | Cenerimod ( ACT-334441 ) |
|---|---|
| Iupac 化学名称 | (S)-3-(4-(5-(2-cyclopentyl-6-methoxypyridin-4-yl)-1,2,4-oxadiazol-3-yl)-2-ethyl-6-methylphenoxy)propane-1,2-diol |
| 同义词 | ACT-334441; ACT334441; ACT 334441; Cenerimod |
| 英文同义词 | ACT-334441; ACT334441; ACT 334441; Cenerimod |
| 分子式 | C25H31N3O5 |
| 分子量 | 453.53 |
| Smile | OC[C@H](O)COC1=C(C)C=C(C2=NOC(C3=CC(C4CCCC4)=NC(OC)=C3)=N2)C=C1CC |
| InChiKey | KJKKMMMRWISKRF-FQEVSTJZSA-N |
| InChi | InChI=1S/C25H31N3O5/c1-4-16-10-18(9-15(2)23(16)32-14-20(30)13-29)24-27-25(33-28-24)19-11-21(17-7-5-6-8-17)26-22(12-19)31-3/h9-12,17,20,29-30H,4-8,13-14H2,1-3H3/t20-/m0/s1 |
| Cas号 | 1262414-04-9 |
| 相关CAS号 | 1262414-04-9 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
|---|---|---|---|---|
| 大货 | 询价 | 询价 | 询价 |
| 外观性状 | Off-white solid |
|---|---|
| 纯度 | ≧98.0% |
| 存储 | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| 可溶性 | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| 处理方式 | Refer to MSDS |
| 运输条件 | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| 海关编码 | 2934200090 |
Coming soon.
| Targets | Cenerimod is a potent, orally active, selective S1P1 receptor modulator. |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
