CRT0273750
Catalog No: 20258
CAS Number: 1979939-16-6
Purity: ≧98.0%
CRT0273750 modulates LPA levels in plasma and is suitable for in vivo studies.
仅供研究使用。 我们不向患者出售。
Chemical Information
| Name | CRT0273750 |
|---|---|
| Iupac Chemical Name | (S)-N-(1-(4-chlorophenyl)ethyl)-3-(3-(4-(trifluoromethoxy)benzyl)-3H-imidazo[4,5-b]pyridin-2-yl)propanamide |
| Synonyms | CRT0273750 ; CRT 0273750 ; CRT-0273750 |
| 英文同义词 | CRT0273750 ; CRT 0273750 ; CRT-0273750 |
| Molecular Formula | C25H22ClF3N4O2 |
| Molecular Weight | 502.92 |
| Smile | FC(F)(F)OC1=CC=C(CN2C(CCC(N[C@@H](C)C3=CC=C(C=C3)Cl)=O)=NC4=CC=CN=C42)C=C1 |
| InChiKey | HXYXHSDYBDFOFO-INIZCTEOSA-N |
| InChi | InChI=1S/C25H22ClF3N4O2/c1-16(18-6-8-19(26)9-7-18)31-23(34)13-12-22-32-21-3-2-14-30-24(21)33(22)15-17-4-10-20(11-5-17)35-25(27,28)29/h2-11,14,16H,12-13,15H2,1H3,(H,31,34)/t16-/m0/s1 |
| CAS Number | 1979939-16-6 |
| 相关CAS号 | 1979939-16-6 |
Ordering Information
| 包装 | Price | 库存 | Purity | 备货期 |
|---|---|---|---|---|
| 大货 | Enquiry | Enquiry | Enquiry |
| 外观性状 | 类白色固体粉末 |
|---|---|
| Purity | ≧98.0% |
| Storage | 短期（几天到几周）为0-4摄氏度，长期（几个月）为-20摄氏度 |
| Solubility | 可溶于DMSO |
| 处理方式 | Avoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation. |
| Shipping Condition | 作为非危险化学品在环境温度下装运。这种产品在正常运输和海关工作期间可以稳定几周 |
| 海关编码 |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
1: Shah P, Cheasty A, Foxton C, Raynham T, Farooq M, Gutierrez IF, Lejeune A, Pritchard M, Turnbull A, Pang L, Owen P, Boyd S, Stowell A, Jordan A, Hamilton NM, Hitchin JR, Stockley M, MacDonald E, Quesada MJ, Trivier E, Skeete J, Ovaa H, Moolenaar WH, Ryder H.
Discovery of potent inhibitors of the lysophospholipase autotaxin. Bioorg Med Chem Lett. 2016 Nov 15;26(22):5403-5410. doi: 10.1016/j.bmcl.2016.10.036. Epub 2016 Oct 14. PubMed PMID: 27780639.
