SAR260301是强有力的和选择性组 I 磷脂酰肌醇-3-激酶(PI3K)β特定抑制剂的同种型,IC50值为52 nM。
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| Name | SAR260301 |
|---|---|
| Iupac Chemical Name | (S)-2-(2-(2-methylindolin-1-yl)-2-oxoethyl)-6-morpholinopyrimidin-4(3H)-one |
| Synonyms | SAR260301; SAR260301; SAR 260301. |
| Molecular Formula | C19H22N4O3 |
| Molecular Weight | 354.40298 |
| Smile | O=C1NC(CC(N2[C@@H](C)CC3=C2C=CC=C3)=O)=NC(N4CCOCC4)=C1 |
| InChiKey | UAXHPOBBKRWJGA-ZDUSSCGKSA-N |
| InChi | InChI=1S/C19H22N4O3/c1-13-10-14-4-2-3-5-15(14)23(13)19(25)11-16-20-17(12-18(24)21-16)22-6-8-26-9-7-22/h2-5,12-13H,6-11H2,1H3,(H,20,21,24)/t13-/m0/s1 |
| CAS Number | 1260612-13-2 |
| Related CAS |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | 类白色至白色固体 |
|---|---|
| Purity | >98% |
| Storage | 短期可在0-4度保存,数天至数月;长期可在-20度保存三年。 |
| Solubility | 可溶于DMSO |
| Handling | |
| Shipping Condition | 可在常温下运输 |
| HS Code |
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| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |