AG-494, also known as Tyrphostin AG-494, is an inhibitor of epidermal growth factor receptor kinase with an IC50 value of 1 µM in HT-22 cells.
For research use only. We do not sell to patients.
Chemical Information
| Name | AG-494 |
| Iupac Chemical Name | 2E-cyano-3-(3,4-dihydroxyphenyl)-N-phenyl-2-propenamide |
| Synonyms | AG-494; AG 494; AG494; |
| Molecular Formula | C16H12N2O3 |
| Molecular Weight | 280.283 |
| Smile | O=C(NC1=CC=CC=C1)/C(C#N)=C/C2=CC=C(O)C(O)=C2 |
| InChiKey | HKHOVJYOELRGMV-XYOKQWHBSA-N |
| InChi | InChI=1S/C16H12N2O3/c17-10-12(8-11-6-7-14(19)15(20)9-11)16(21)18-13-4-2-1-3-5-13/h1-9,19-20H,(H,18,21)/b12-8+ |
| CAS Number | 133550-35-3 |
| Related CAS | |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
| Bulk | | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white solid to white solid |
| Purity | >98% |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code | |
| Targets | |
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study | |