AG-494 Catalog No : 186273

Product Name	AG-494
Iupac Chemical Name	2E-cyano-3-(3,4-dihydroxyphenyl)-N-phenyl-2-propenamide
Synonyms	AG-494; AG 494; AG494;
Molecular Formula	C16H12N2O3
Molecular Weight	280.283
Smile	O=C(NC1=CC=CC=C1)/C(C#N)=C/C2=CC=C(O)C(O)=C2
InChiKey	HKHOVJYOELRGMV-XYOKQWHBSA-N
InChi	InChI=1S/C16H12N2O3/c17-10-12(8-11-6-7-14(19)15(20)9-11)16(21)18-13-4-2-1-3-5-13/h1-9,19-20H,(H,18,21)/b12-8+
Cas	133550-35-3

Appearance	Off-white solid to white solid
Purity	>98%
Solubility	Soluble in DMSO
Storage	Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Shipping Condition	Shipped under ambient temperature
Quality control

AG-494, also known as Tyrphostin AG-494, is an inhibitor of epidermal growth factor receptor kinase with an IC50 value of 1 µM in HT-22 cells.

Chemical Structure