AST487
Catalog No: 186158
CAS Number: 630124-46-8
Purity: >98%
AST487, also known as NVP- AST487, is a RET kinase inhibitor/FLT3 inhibitor.
For research use only. We do not sell to patients.
Chemical Information
| Name | AST487 |
|---|---|
| Iupac Chemical Name | 1-(4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-(4-((6-(methylamino)pyrimidin-4-yl)oxy)phenyl)urea |
| Synonyms | NVPAST487; AST 487; AST487; AST-487. |
| Molecular Formula | C26H30F3N7O2 |
| Molecular Weight | 529.56 |
| Smile | O=C(NC1=CC=C(OC2=NC=NC(NC)=C2)C=C1)NC3=CC=C(CN4CCN(CC)CC4)C(C(F)(F)F)=C3 |
| InChiKey | ODPGGGTTYSGTGO-UHFFFAOYSA-N |
| InChi | InChI=1S/C26H30F3N7O2/c1-3-35-10-12-36(13-11-35)16-18-4-5-20(14-22(18)26(27,28)29)34-25(37)33-19-6-8-21(9-7-19)38-24-15-23(30-2)31-17-32-24/h4-9,14-15,17H,3,10-13,16H2,1-2H3,(H,30,31,32)(H2,33,34,37) |
| CAS Number | 630124-46-8 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white solid to white solid |
|---|---|
| Purity | >98% |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
