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Membrane Transporter/Ion Channel
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
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NF-κB
Protein Tyrosine Kinase
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Cas Index 1
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Cas Index 1
1450881-55-6 | SAR-20347
(Catalog# : 1781101)
SAR-20347 is a potent dual inhibitor of JAK1 and tyrosine kinase 2 (TYK2).
1523406-39-4 | SAR-405
(Catalog# : 2017882)
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148554-65-8 | Seco Rapamycin (sodium salt)
(Catalog# : 20177313)
Seco-rapamycin is the first in vivo open-ring metabolite of rapamycin that does not a
1184843-57-9 | SAR-020106
(Catalog# : 17031004)
SAR-020106 is an ATP-competitive, potent, and selective CHK1 inhibitor with an IC50
1456632-41-9 | SH5-07
(Catalog# : 17031002)
SH5-07 is a robust hydroxamic acid-based STAT3 inhibitor, which induce antitumor ce
138794-73-7 | Sardomozide HCl
(Catalog# : 17030306)
Sardomozide , also known as SAM486A or CGP48664, is a second-generation polyamine syn
149690-05-1 | Sacubitril sodium
(Catalog# : 17030108)
Sacubitril, also known as AHU377, is angiotensin receptor neprilysin inhibitor being
1801747-42-1 | SHP099 free base
(Catalog# : 17030107)
SHP099 is a potent, selective, orally bioavailable, and efficacious SHP2 inhibitor wi
1431699-67-0 | (S)-Tedizolid
(Catalog# : 17021402)
Tedizolid is the active moiety of the prodrug tedizolid phosphate, with high potency
1265965-22-7 | S49076
(Catalog# : 17021309)
S49076 is a novel, potent inhibitor of MET, AXL/MER, and FGFR1/2/3 with IC50 valu
1001908-89-9 | SRT2183
(Catalog# : 17021306)
SRT2183 is a small-molecule activator of the sirtuin subtype SIRT1, currently being
18883-66-4 | Streptozocin
(Catalog# : 17011712)
Streptozocin is a methylnitrosourea antineoplastic antibiotic isolated from the bacte
1018899-04-1 | Sotagliflozin
(Catalog# : 17011711)
Sotagliflozin, also known as LX4211, is an orally active and a dual SGLT1/SGLT2 inhib
127254-12-0 | Sitafloxacin anhydrous
(Catalog# : 17011706)
Sitafloxacin is a new-generation, broad-spectrum oral fluoroquinolone that is very ac
1801747-11-4 | SHP099 HCl
(Catalog# : 17011704)
SHP099 is a potent, selective, orally bioavailable, and efficacious SHP2 inhibitor wi
1687736-54-4 | SGC707
(Catalog# : 17011702)
SGC707 is a potent, selective and cell-active allosteric inhibitor of protein arginin
1884220-36-3 | SBI0206965
(Catalog# : 71161)
SBI0206965 is a potent and selective autophagy Kinase ULK1 Inhibitor. Many tumors bec
149400-88-4 | Sardomozide
(Catalog# : 17011607)
Sardomozide , also known as SAM486A or CGP48664, is a second-generation polyamine syn
1092539-44-0 | SAR131675
(Catalog# : 17011605)
SAR131675 is a potent and selective VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine
127373-66-4 | Sivelestat (ONO-5046)
(Catalog# : 16122760)
Sivelestat is a potent and selective inhibitor of neutrophil elastase with IC50 of 44
17318-31-9 | SQ22536
(Catalog# : 16122726)
SQ22536 is an inhibitor of adenylyl cyclase with an IC50 of 1.4 M. It can inhibit PGE
111540-00-2 | STA-21
(Catalog# : 16122706)
STA-21 is a selective STAT3 inhibitor.In cells, STA-21 inhibits Stat3 DNA binding act
1335106-03-0 | SR1001
(Catalog# : 6111522)
SR1001 is a selective ROR and ROR inverse agonist; suppresses TH17 cell differentiati
1324003-64-6 | S1P1 Agonist III
(Catalog# : 61119)
S1P1 Agonist III is a potent and orally active S1P1 agonist with EC50 of 18 nM; no ac
1186222-89-8 | 4SC-202
(Catalog# : 611937)
4SC-202 is an orally available potent HDACi specific for class I HDAC isoenzymes(NO H
1454585-06-8 | SR-3029
(Catalog# : 611915)
SR 3029 is a potent and highly specific CK1/CK1 inhibitor with the IC50 of 97 nM.SR-3
1456632-40-8 | SH-4-54
(Catalog# : 16071406)
SH-4-54 is a potent STAT inhibitor with KD of 300 nM and 464 nM for STAT3 and STAT5,
1230487-00-9 | Siponimod
(Catalog# : 16071404)
Siponimod, also known as BAF-312, is a a potent and orally selective S1P Receptor Mod
1116743-46-4 | SAR125844
(Catalog# : 16071023)
SAR125844 is a potent and highly selective c-Met inhibitor with potential antineoplas
1093403-33-8 | SRT2104
(Catalog# : 16071014)
SRT2104, also known as GSK2245840, is a novel, first-in-class, highly selective small
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
2377000-84-3 | Dencatistat
(Catalog# : 25177)
Dencatistat is an orally bioavailable, small molecule inhibitor of cytidine triphosph
1898207-64-1 | DS-1001b
(Catalog# : 25178)
DS-1001 is an oral brain-penetrant mutant IDH1 selective inhibitor.
1016340-64-9 | Z57346765
(Catalog# : 25191)
Z57346765 is a PGK1-specific inhibitor that reduces the activity of metabolic enzymes
2416095-06-0 | CBR-470-1
(Catalog# : 25192)
CBR-470-1 is an Inhibitor of the glycolytic enzyme PGK1that induces Nrf2 activity.
1898206-17-1 | Safusidenib
(Catalog# : 25149)
Safusidenib, also known as DS-1001, is an oral isocitrate dehydrogenase [NADP] cytopl
2803470-63-3 | HC-7366
(Catalog# : 25076)
HC-7366 is a potent and selective activator of the general control nonderepressible 2
146426-40-6 | Flavopiridol ( Alvocidib )
(Catalog# : 237071)
Alvocidib is a synthetic dihydroxyflavone that is 5,7-dihydroxyflavone which is subst
2201056-66-6 | AG-270
(Catalog# : 25176)
MAT2A Inhibitor AG-270 is an orally available small molecule inhibitor of methionine
618913-30-7 | AZD-5904
(Catalog# : 181121)
AZD5904 is a potent orally bioavailable MPO inhibitor. In preclinical studies, AZD590
2035010-37-6 | ALT-007
(Catalog# : 25157)
ALT-007 is an orally bioavailable SPT inhibitor that is more potent than myriocin, sa