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Amines
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Boronic Acids
Bromides
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Deuterated
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+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
Microbiology
Others
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
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On Sale
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联系我们
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Cas号索引 9
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Cas号索引 9
945714-67-0 | FPS-ZM1
(Catalog# : 16123002)
FPS-ZM1 is a high-affinity RAGE-specific blocker that inhibits amyloid- binding to RA
957485-64-2 | FPH2
(Catalog# : 032513)
Coming soon!
936091-26-8 | Fedratinib ( TG-101348 )
(Catalog# : 122306)
Fedratinib ( TG-101348 ) is a selective inhibitor of JAK2 with IC50 of 3 nM, 35- and
938435-69-9 | Flobetair
(Catalog# : 102904)
Coming soon!
939055-18-2 | FIPI
(Catalog# : 102617)
FIPI is a derivative of halopemide which potently inhibits both PLD1 (IC50 = 25 nM) a
942206-85-1 | GSK1016790A
(Catalog# : 2071511)
GSK1016790A, also known as GSK101, is a TRPV4 agonist that elicits calcium influx in
901245-65-6 | GSK-5959
(Catalog# : 1811266)
GSK-5959是一种有效的选择性BRPF1溴域抑制剂(IC50 = 80 nM)。
937174-76-0 | GSK-690693
(Catalog# : 161009019)
Pan-AKT kinase inhibitor GSK-690693 binds to and inhibits Akt kinases 1, 2, and 3, wh
929095-18-1 | GSK-461364
(Catalog# : 16071032)
GSK-461364 is a Polo-like kinase 1 inhibitor, is also a small molecule Polo-like kina
936694-12-1 | Glesatinib(MGCD-265)
(Catalog# : 012001)
Glesatinib is a potent tyrosine kinase inhibitor with potential antineoplastic activi
937812-80-1 | Gamma-Secretase Modulators
(Catalog# : 011909)
Coming soon!
957054-30-7 | GDC-0941
(Catalog# : 120115)
GDC-0941 is a potent inhibitor of PI3K/ with IC50 of 3 nM, with modest selectivity ag
942918-07-2 | GSK-1070916
(Catalog# : 111011)
GSK1070916 is a reversible and ATP-competitive inhibitor of Aurora B/C with IC50 of 3
958852-01-2 | GSK1059615
(Catalog# : 52628)
GSK1059615 is a dual inhibitor of PI3K/// (reversible) and mTOR with IC50 of 0.4 nM/0
928037-13-2 | Golvatinib (E7050)
(Catalog# : 52020)
Golvatinib (E7050) is a dualc-MetandVEGFR-2inhibitor with IC50 of 14 nM and 16 nM, do
924296-39-9 | HBX-41108
(Catalog# : 19317)
HBX 41108是泛素特异性蛋白酶(USP) 7的抑制剂。HBX 41108通过IC(50)在亚
941987-60-6 | H 151
(Catalog# : 1811022)
H 151是一种诱捕拮抗剂,共价结合在Cys91上,阻断棕榈酰化和防止
934343-74-5 | HSP990 (NVP-HSP990)
(Catalog# : 52015)
NVP-HSP990 (HSP990) is a novel, potent and selectiveHSP90inhibitor for HSP90/ withIC5
942123-43-5 | Inarigivir soproxil
(Catalog# : 186277)
Inarigivir soproxil,也被称为SB 9200,是一种抗病毒药物。
901751-47-1 | iCRT3
(Catalog# : 18492)
iCRT3是Wnt/β-catenin信号的拮抗剂,在Wnt responsive STF16-luc reporter assay
945526-43-2 | ISCK03
(Catalog# : 1791118)
ISCK03是一种有效的c-kit抑制剂。ISCK03抑制在501mel人黑素瘤细胞的SC
914638-30-5 | IDO-IN-1
(Catalog# : 16122822)
IDO-IN-1 is a potent and selective indoleamine-2,3-dioxygenase (IDO) inhibitor with I
937263-43-9 | Irbinitinib
(Catalog# : 011310)
Irbinitinib is a potent and selective HER2 inhibitor with IC50 of 8 nM, equipotent ag
914471-09-3 | IDO-IN-2
(Catalog# : 123002)
IDO-IN-2 is a potent IDO1 inhibitor(IC50=10 nM) with desirable pharmaceutical propert
99059-64-0 | 3-iodo-4-isopropylbenzoic acid
(Catalog# : 80313)
Coming soon!
931398-72-0 | IOX2
(Catalog# : 52527)
IOX2 is a selective inhibitor of the Hypoxia Inducible Factor (HIF) Prolyl-Hydroxylas
943540-74-7 | JNJ-38877618
(Catalog# : 204307)
JNJ-38877618 is a hepatocyte growth factor receptor (HGFR; MET; c-Met) inhibitor pote
900573-88-8 | JI-101
(Catalog# : 16122823)
JI-101 is an orally active inhibitor of vascular endothelial growth factor receptor 2
952849-76-2 | KKL-10
(Catalog# : 184217)
KKL-10是一种抗菌药物。KKL-10在体外和体外感染中均表现出了对弱毒
927822-86-4 | KC7F2
(Catalog# : 16122827)
KC7F2 is a potent HIF-1 pathway inhibitor with potential anticancer activity. KC7F2 i
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产品分类
信号通路
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
----
NEKs
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
----
GLP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
----
Lactate dehydrogenase
----
Glyoxalase (GLO)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
1497439-74-3 | AD-8007
(Catalog# : 26A018)
AD-8007是一种选择性且可穿透血脑屏障的乙酰辅酶A合成酶2(ACSS2)
1802650-31-2 | ZY-444
(Catalog# : 26A020)
ZY-444是一种通过抑制PC活性发挥抗癌作用的药物。
2306525-79-9 | AD-5584
(Catalog# : 26A019)
AD-5584是一种新型脑渗透性ACSS2抑制剂。
3079716-11-0 | IDB-003
(Catalog# : 26A017)
IDB-003在体内抑制MDA-MB-231肿瘤生长。
1357362-02-7 | Vafidemstat
(Catalog# : 18891)
Vafidemstat又称ORY 2001,是一种赖氨酸特异性组蛋白去甲基化酶(LSD1)
1260247-42-4 | LLL12
(Catalog# : 25075)
LLL12是一种强效的STAT3抑制剂。LLL12在小鼠异种移植物模型中显示出
2758659-09-3 | ECC-5004
(Catalog# : 26A015)
ECC5004是一款每日一次、低剂量、小分子GLP-1受体激动剂。
2911585-37-8 | SILA-123
(Catalog# : 26A014)
SILA-123是一种II型FLT3抑制剂,对FLT3-WT(IC50=2.1 nM)和FLT3-ITD(IC50=1
1214922-52-7 | Encaleret sulfate
(Catalog# : 26A013)
Encaleret是一种正在研究的钙敏感受体的小分子拮抗剂,用于钙稳态
1431303-72-8 | Iadademstat ( ORY-1001 ) hydrochloride
(Catalog# : 26A011)
Iadademstat(ORY-1001)是一种口服活性、高效和选择性的表观遗传酶