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首页
抑制剂/受体激动剂
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
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Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
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Cas号索引 9
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Cas号索引 9
92953-10-1 | 氯非铵甲苯磺酸盐
(Catalog# : 193181)
氯非铵甲苯磺酸盐是一种K+通道阻滞剂、心脏抑制剂和抗心律失常
942947-93-5 | CCT129202
(Catalog# : 1810291)
CCT129202是Aurora激酶活性的抑制剂,在临床前研究中表现出良好的抗
902146-11-6 | CBM 301940
(Catalog# : 1810232)
CBM 301940是一种有效的丙二酰辅酶a脱羧酶抑制剂,具有口服生物有
97519-39-6 | 头孢布烯
(Catalog# : 17032405)
头孢布烯(Sch39720)是第三代头孢菌素类抗生素。
944808-88-2 | CAY 10566
(Catalog# : 10403)
CAY 10566是一种强效的选择性SCD-1抑制剂。
934240-30-9 | CNV1014802
(Catalog# : 122812)
CNV1014802 is a novel small molecule state-dependent sodium channel blocker; Nav1.7 s
934660-93-2 | Cobimetinib
(Catalog# : 102203)
Cobimetinib is an orally bioavailable small-molecule inhibitor of mitogen-activated p
910232-84-7 | CGI-1746
(Catalog# : 73103)
CGI1746 is a potent and highly selective small-molecule inhibitor of the Btk with IC5
905973-89-9 | CGK 733
(Catalog# : 51917)
CGK 733 is a potent and selective inhibitor ofATM/ATRwithIC50of ~200 nM.
95809-78-2 | CPI-613(Devimistat )
(Catalog# : 51905)
CPI-613( Devimistat ) is an E1 pyruvate dehydrogenase (PDH) modulator that prevents c
960069-34-5 | 5-氘代-2,4-二溴噻唑
(Catalog# : 24060)
911115-16-7 | Decoglurant
(Catalog# : 2071542)
Decoglurant, also known as Ro 4995819, is a negative allosteric modulator of the mGlu
93701-32-7 | 1,3-Dibromo-2-(bromomethyl)benzene
(Catalog# : 2062308)
960539-70-2 | Daprodustat (Synonyms: GSK1278863)
(Catalog# : 112596)
Daprodustat (Synonyms: GSK1278863) is an orally active hypoxia-inducible factor proly
934246-14-7 | Degarelix acetate
(Catalog# : 192262)
Degarelix, 也称为FE-200486和ASP-3550,是一种具有促性腺激素释放激素
915769-50-5 | 多韦替尼乳酸盐
(Catalog# : 18575)
多韦替尼,也称为TKI-258或CHIR-258,是一种口服生物药效应的FGFR3抑制
954126-98-8 | Danirixin
(Catalog# : 16111111)
Danirixin is a small molecule, non-peptide, high affinity (IC50 for CXCL8 binding = 1
90332-63-1 | 10-Deacetyl-7-xylosyl paclitaxel
(Catalog# : 611946)
10-Deacetyl-7-xylosyl paclitaxel is a Paclitaxel derivative with improved pharmacolog
924296-17-3 | DUBs-IN-3
(Catalog# : 611929)
DUBs-IN-3 is a potent deubiquitinase enzyme inhibitor with IC50s of 3.1 uM for USP8;
924296-18-4 | DUBs-IN-1
(Catalog# : 611928)
DUBs-IN-1 is a potent deubiquitinase enzyme inhibitor with IC50s of 18 uM/0.71 uM for
917918-79-7 | 4,7-dimethoxy-1H-pyrrolo[2,3-c]pyridine,hydrochloride
(Catalog# : 92214)
Coming soon!
944842-54-0 | Decernotinib(VX-509)
(Catalog# : 90733)
Decernotinib(VX-509) may potently inhibits JAK3 in enzyme assays (Ki = 2.5 nM + 0.7 n
90604-02-7 | 1-(Diphenylmethyl)-3-Hydroxyazetidine Hydrochloride
(Catalog# : 83116)
Coming soon!
929046-33-3 | Elinzanetant ( NT-814 )
(Catalog# : 20259)
Elinzanetant,以前称为 NT-814 (45),是一种双重 NK1,3R 拮抗剂,因此有
945531-77-1 | Ezutromid
(Catalog# : 16122944)
Ezutromid, also known as BMN-195 and SMTC-1100, is a first orally bioavailable utroph
91119-27-6 | ethyl 5-chloro-7-nitro-1H-indole-2-carboxylate
(Catalog# : 5121008)
ethyl 5-chloro-7-nitro-1H-indole-2-carboxylate,CAS#91119-27-6
923978-27-2 | Elafibranor (GFT505)
(Catalog# : 5112801)
Elafibranor (GFT505) 是 PPARα/δ 的激动剂,EC50 分别为 45 和 175 nM。目前
934353-76-1 | ENMD-2076
(Catalog# : 111909)
ENMD-2076 has selective activity against Aurora A and Flt3 with IC50 of 14 nM and 1.8
90176-80-0 | 4-氟-2-(三氟甲基)苯甲醛
(Catalog# : 20405)
932737-65-0 | FITM
(Catalog# : 17989)
FITM是一种有效的mGlu1 抑制剂。
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产品分类
信号通路
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
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--
Chiral Compounds
--
Deuterated
--
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On Sale
新产品
天然化合物
最新产品
2351225-46-0 | NSD1 抑制剂 BT5
(Catalog# : 25207)
BT5可有效抑制NSD1,与细胞中的SET结构域结合,并降低H3K36me2水平。
1049704-18-8 | MA242 TFA
(Catalog# : 25206)
MA242是一种MDM2和NFAT1双重抑制剂,可诱导MDM2自泛素化及降解,并抑
2800223-30-5 | Dabogratinib ( TYRA-300 )
(Catalog# : 24073)
Dabogratinib ( TYRA-300 )是一种口服选择性成纤维细胞生长因子受体3(
N/A | AF710B
(Catalog# : 25205)
AF710B 是一种高效、选择性变构 M1 毒蕈碱和 σ1 受体激动剂。 AF710
2957874-18-7 | MAT2A inhibitor 5
(Catalog# : 25204)
MAT2A抑制剂5具有抑制MAT2A的高效力和对MTAP缺失的癌症细胞系的显著
1235733-73-9 | (Rac)-AF710B
(Catalog# : 24083)
AF-710B 是 σ 和 M1 毒蕈碱受体的激动剂;AF710B 是 AF710 的对映体。
863888-33-9 | Flurpiridaz-nonradiolabeled
(Catalog# : 25203)
Flurpiridaz是一种有前景的新型心脏PET成像示踪剂,是通过用氟-18放
863888-32-8 | Flurpiridaz-Precursor
(Catalog# : 25202)
现货
1800405-30-4 | KL1333
(Catalog# : 25201)
KL1333是一种口服的小有机分子,与NAD(P)H:醌氧化还原酶1(NQO1)
1369489-71-3 | Palupiprant ( E7046 )
(Catalog# : 24055)
E7046 is a potent and selective antagonist of the type 4 prostaglandin E2 (PGE2) rece