FPS-ZM1
编号: 16123002
Cas号: 945714-67-0
纯度: 98%
FPS-ZM1 is a high-affinity RAGE-specific blocker that inhibits amyloid- binding to RAGE, neurological damage and inflammation in the APP(sw/0) transgenic mouse model of AD. FPS-ZM1 is not toxic to mice and can easily cross the blood-brain barrier. AGEs administration induced an-regulation of Abeta production, inflammation, and oxidative stress, and an increased escape latency of rats in the Morris water maze test, all of these are significantly reduced by FPS-ZM1 treatment. FPS-ZM1 might be a novel therapeutic agent to treat AD patients.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | FPS-ZM1 |
|---|---|
| Iupac 化学名称 | FPS-ZM1 |
| 同义词 | N/A |
| 英文同义词 | N/A |
| 分子式 | C20H22ClNO |
| 分子量 | 327.852 |
| Smile | C1C(C(N(C2CCCCC2)CC2C=CC=CC=2)=O)=CC=C(Cl)C=1 |
| InChiKey | XDFKWGIBQMHSOH-UHFFFAOYSA-N |
| InChi | InChI=1S/C20H22ClNO/c21-18-13-11-17(12-14-18)20(23)22(19-9-5-2-6-10-19)15-16-7-3-1-4-8-16/h1,3-4,7-8,11-14,19H,2,5-6,9-10,15H2 |
| Cas号 | 945714-67-0 |
| 相关CAS号 |
订购信息
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| 大货 | 询价 | 询价 | 询价 |
