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+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
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NF-κB
Protein Tyrosine Kinase
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Pyrimidines
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Cas号索引 1
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Cas号索引 1
1143532-39-1 | Capivasertib ( AZD5363 )
(Catalog# : 71805)
Capivasertib是一种新型的吡咯并嘧啶衍生物,是一种可口服的丝氨酸
1374640-70-6 | CO-1686(Rociletinib)
(Catalog# : 60701)
CO-1686(Rociletinib) is an irreversible inhibitor of epidermal growth factor receptor
135463-81-9 | Coluracetam
(Catalog# : 52782)
Coluracetam(MKC-231) is a new choline uptake enhancer.
1369761-01-2 | Cerdulatinib (PRT062070, PRT2070)
(Catalog# : 52780)
Cerdulatinib (PRT-062070) is an oral active, multi-targeted tyrosine kinase inhibitor
1140909-48-3 | Cabozantinib S-malate
(Catalog# : 52778)
Cabozantinib S-malate (XL184, BMS-907351) is a potent VEGFR2 inhibitor with IC50 of 0
1138549-36-6 | CX-5461
(Catalog# : 52748)
CX-5461 is an inhibitor of rRNA synthesis, selectively inhibits Pol I-driven transcri
1159824-67-5 | CZC24832
(Catalog# : 52735)
CZC24832 is a selective inhibitor of PI 3-kinase (IC50 = 1.0 M in a PI 3-K-dependent
1045792-66-2 | CAY10603
(Catalog# : 52705)
CAY10603 is a potent and selective inhibitor of HDAC6 with IC50 of 2 pM, as compared
1256963-02-6 | CDK4-IN-1
(Catalog# : 52610)
CDK4 inhibitor is a novel and specific CDK4/Cyclin D1 inhibitor with an IC50 of 10 nM
1191911-27-9 | CZC-54252
(Catalog# : 52566)
CZC-54252 is a potent inhibitor of LRRK2 with IC50s of 1.28 nM and 1.85 nM for wild-t
1056634-68-4 | CYT387
(Catalog# : 52534)
CYT387(momelotinib) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/1
112522-64-2 | CI-994
(Catalog# : 52517)
CI-994 (Tacedinaline) is an anti-cancer drug which inhibits HDAC1 with IC50 of 0.57 M
1439934-41-4 | CTX-0294885
(Catalog# : 52213)
CTX-0294885 is a a novel bisanilino pyrimidine; exhibits inhibitory activity against
1202916-90-2 | CX-6258
(Catalog# : 52234)
CX-6258 is a potent, orally efficacious Pim 1/2/3 kinase(IC50=5 nM/25 nM/16 nM) inhib
1256589-74-8 | CH5424802 Hydrochloride
(Catalog# : 51606)
CH5424802 Hcl (AF 802 Hcl; Alectinib Hcl) is a potent ALK inhibitor with IC50 of 1.9
1009820-21-6 | CX-4945(Silmitasertib)
(Catalog# : 52024)
Silmitasertib (CX-4945) is a potent and selective orally bioavailable small molecule
1004316-88-4 | Cobicistat(GS-9350)
(Catalog# : 51906)
Cobicistat is a potent inhibitor of cytochrome P450 3A enzymes, including the importa
1898207-64-1 | DS-1001b
(Catalog# : 25178)
DS-1001 是一种口服的脑渗透性突变 IDH1 选择性抑制剂。
1784086-71-0 | 5,7-二氟-3-甲基苯并呋喃-2-甲醛
(Catalog# : 25129)
146255-66-5 | DHPG
(Catalog# : 25056)
DHPG, also known as (RS)-3,5-DHPG, is a selective agonist for group I metabotropic gl
1516679-30-3 | 6-氰基-1,3-二甲基-1H-吲唑
(Catalog# : 25037)
1413431-07-8 | Deutivacaftor
(Catalog# : 24096)
Deutivacaftor, also known as CTP-656 and VX561, is a cystic fibrosis transmembrane co
1399177-37-7 | Denifanstat
(Catalog# : 20596)
TVB-2640 is an orally bioavailable fatty acid synthase (FASN) inhibitor, with potenti
1932352-50-5 | 1,1-Dimethylethyl (1S,5S)-1-formyl-3-azabicyclo[3.1.0]hexane-3-carboxylate
(Catalog# : 20545)
1932410-93-9 | 1,1-Dimethylethyl (1R,5S)-1-ethynyl-3-azabicyclo[3.1.0]hexane-3-carboxylate
(Catalog# : 20544)
1932534-25-2 | (1S,5S)-1-(羟甲基)-3-氮杂双环[3.1.0]己烷-3-羧酸叔丁酯
(Catalog# : 20543)
1059070-10-8 | DSR-6434
(Catalog# : 20497)
DSR-6434 is a potent TLR7 agonist (EC50 = 7.2 nM). DSR-6434 activates several immune
1203494-49-8 | DASA-58
(Catalog# : 20489)
DASa-58, also known as ML-203 and NCGC00185916, is a selective activator of pyruvate
178803-91-3 | DC-S100
(Catalog# : 20456)
DC-S100 is a selective histone methyltransferase SET7 inhibitor.
122509-73-3 | 4,5-二氯吲哚
(Catalog# : 20442)
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产品分类
信号通路
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
85622-93-1 | Temozolomide
(Catalog# : 25209)
替莫唑胺是一种烷化剂。
2035010-37-6 | ALT-007
(Catalog# : 25157)
ALT-007 是一种口服生物可利用的 SPT 抑制剂,比多球菌素更有效,
2376397-93-0 | Opakalim
(Catalog# : 25193)
Opakalim(BHV-7000)是Kv7.2/7.3钾通道(KCNQ2/3)的口服小分子激活剂,
2102501-84-6 | PF-06835919 ( MDK-1846 )
(Catalog# : 193264)
MDK1846是一种强效的酮己糖激酶(KHK)抑制剂。
2271348-04-8 | MK256
(Catalog# : 25208)
MK256是一种新型CDK8抑制剂,通过下调STAT通路在急性髓系白血病(
2351225-46-0 | NSD1 抑制剂 BT5
(Catalog# : 25207)
BT5可有效抑制NSD1,与细胞中的SET结构域结合,并降低H3K36me2水平。
1049704-18-8 | MA242 TFA
(Catalog# : 25206)
MA242是一种MDM2和NFAT1双重抑制剂,可诱导MDM2自泛素化及降解,并抑
2800223-30-5 | Dabogratinib ( TYRA-300 )
(Catalog# : 24073)
Dabogratinib ( TYRA-300 )是一种口服选择性成纤维细胞生长因子受体3(
N/A | AF710B
(Catalog# : 25205)
AF710B 是一种高效、选择性变构 M1 毒蕈碱和 σ1 受体激动剂。 AF710
2957874-18-7 | MAT2A inhibitor 5
(Catalog# : 25204)
MAT2A抑制剂5具有抑制MAT2A的高效力和对MTAP缺失的癌症细胞系的显著