武汉永璨生物科技有限公司
+86-17702719238 sales@sun-shinechem.com

CCT244747

编号: 16070913
Cas号: 1404095-34-6
纯度: 98% by HPLC 

CCT244747 is a novel potent, highly selective, orally active ATP-competitive CHK1 inhibitor with potential anticancer activity. CCT244747 inhibited cellular CHK1 activity (IC(50) 29-170 nmol/L), significantly enhanced the cytotoxicity of several anticancer drugs, and abrogated drug-induced S and G(2) arrest in multiple tumor cell lines. CCT244747 represents the first structural disclosure of a highly selective, orally active CHK1 inhibitor and warrants further evaluation alone or combined with genotoxic anticancer therapies. 

仅供研究使用。 我们不向患者出售。

化学信息

名称CCT244747
Iupac 化学名称(R)-3-((1-(dimethylamino)propan-2-yl)oxy)-5-((4-methoxy-5-(1-methyl-1H-pyrazol-4-yl)pyridin-2-yl)amino)pyrazine-2-carbonitrile 
同义词CCT244747; CCT-244747; 
英文同义词CCT244747; CCT-244747; 
分子式C20H24N8O2 
分子量408.46 
SmileCN(C[C@@H](C)OC=1C(=NC=C(N1)NC1=NC=C(C(=C1)OC)C=1C=NN(C1)C)C#N)C
InChiKeyIENLGMOXAQMNEH-CYBMUJFWSA-N
InChiInChI=1S/C20H24N8O2/c1-13(11-27(2)3)30-20-16(7-21)22-10-19(26-20)25-18-6-17(29-5)15(9-23-18)14-8-24-28(4)12-14/h6,8-10,12-13H,11H2,1-5H3,(H,23,25,26)/t13-/m1/s1
Cas号1404095-34-6
相关CAS号

订购信息

包装价格库存纯度备货期
大货询价询价询价
Request Bulk Quote Download MSDS 电话 : +86-177 0271 9238   Email : sales@sun-shinechem.com
外观性状Solid powder 
纯度98% by HPLC 
存储-20 ºC for 3 years 
可溶性Soluble in DMSO 
处理方式
运输条件Shipped under ambient temperature 
海关编码
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

16070913 - CCT244747 | CAS 1404095-34-6

快速订购

Change