Compound 401
编号: 611816
Cas号: 168425-64-7
纯度: 98%
Compound 401 is a synthetic inhibitor of DNA-PK (IC50 = 0.28 M) that also targets mTOR but not PI3K.
Compound 401 shows activity against mTOR (IC50 = 5.3 M) but not p110/p85 PI3K (IC50 > 100 M). Treatment of cells with Compound 401 blocks the phosphorylation of sites modified by mTOR-Raptor and mTOR-Rictor complexes (ribosomal protein S6 kinase 1 Thr389 and Akt Ser473, respectively).
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | Compound 401 |
|---|---|
| Iupac 化学名称 | Compound 401 |
| 同义词 | Compound-401; Compound401 |
| 英文同义词 | Compound-401; Compound401 |
| 分子式 | C16H15N3O2 |
| 分子量 | 281.31 |
| Smile | c1ccc2c(c1)ccn3c2nc(cc3=O)N4CCOCC4 |
| InChiKey | BVRDQVRQVGRNHG-UHFFFAOYSA-N |
| InChi | InChI=1S/C16H15N3O2/c20-15-11-14(18-7-9-21-10-8-18)17-16-13-4-2-1-3-12(13)5-6-19(15)16/h1-6,11H,7-10H2 |
| Cas号 | 168425-64-7 |
| MDL | MFCD10568147 |
| 相关CAS号 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
|---|---|---|---|---|
| 大货 | 询价 | 询价 | 询价 |
