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Copanlisib

Catalog No.: 16070917
Cas No.: 1032568-63-0
Purity : 98% by HPLC 
16070917 - Copanlisib | CAS 1032568-63-0

Catalog number : 16070917

CAS number : 1032568-63-0

分子式 : C23H28N8O4 

分子量 : 480.52 

Iupac 化学名称 : 2-amino-N-(7-methoxy-8-(3-morpholinopropoxy)-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl)pyrimidine-5-carboxamide 

Smile : NC1=NC=C(C=N1)C(=O)NC1=NC=2C(=C(C=CC2C=2N1CCN2)OCCCN2CCOCC2)OC

InChiKey : PZBCKZWLPGJMAO-UHFFFAOYSA-N

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同义词BAY 80-6946 
英文同义词BAY 80-6946 
分子式C23H28N8O4 
分子量480.52 
外观Solid powder 
纯度98% by HPLC 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileNC1=NC=C(C=N1)C(=O)NC1=NC=2C(=C(C=CC2C=2N1CCN2)OCCCN2CCOCC2)OC
InChiKeyPZBCKZWLPGJMAO-UHFFFAOYSA-N
InChiInChI=1S/C23H28N8O4/c1-33-19-17(35-10-2-6-30-8-11-34-12-9-30)4-3-16-18(19)28-23(31-7-5-25-20(16)31)29-21(32)15-13-26-22(24)27-14-15/h3-4,13-14H,2,5-12H2,1H3,(H2,24,26,27)(H,28,29,32)
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Copanlisib, also known as BAY 80-6946, is a phosphoinositide 3-kinase (PI3K) inhibitor with potential antineoplastic activity. PI3K inhibitor BAY 80-6946 inhibits the activation of the PI3K signaling pathway, which may result in inhibition of tumor cell growth and survival in susceptible tumor cell populations. Activation of the PI3K signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K signaling may contribute to tumor resistance to a variety of antineoplastic agents. 

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