MAT2A-IN-22
Catalog No: 26A021
CAS Number: 2925330-18-1
Purity: ≧98.0%
MAT2A-IN-22 (Compound 29-1) is a blood-brain barrier-penetrant and orally active MAT2A inhibitor. It exhibits selective and inhibitory activity against MTAP-deficient cancer cell lines. MAT2A-IN-22 possesses antitumor effects.
For research use only. We do not sell to patients.
Chemical Information
| Name | MAT2A-IN-22 |
|---|---|
| Iupac Chemical Name | (R)-1'-((methyl-d3)amino)-6'-(trifluoromethyl)-6,7-dihydro-3'H-spiro[cyclopenta[b]pyridine-5,4'-isoquinolin]-3'-one |
| Synonyms | MAT2A-IN-22 |
| Molecular Formula | C18H11D3F3N3O |
| Molecular Weight | 348.13 |
| Smile | O=C([C@@]12CCC3=NC=CC=C31)N=C(NC([2H])([2H])[2H])C4=C2C=C(C(F)(F)F)C=C4 |
| InChiKey | QORHMXRPXOGKGZ-DBHFXHLNSA-N |
| InChi | InChI=1S/C18H14F3N3O/c1-22-15-11-5-4-10(18(19,20)21)9-13(11)17(16(25)24-15)7-6-14-12(17)3-2-8-23-14/h2-5,8-9H,6-7H2,1H3,(H,22,24,25)/t17-/m0/s1/i1D3 |
| CAS Number | 2925330-18-1 |
| Related CAS | 2925330-18-1 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
