BIIB129 is a covalent, selective, small molecule inhibitor of Bruton's tyrosine kinase (BTK) capable of penetrating the blood-brain barrier.
For research use only. We do not sell to patients.
| Name | BIIB-129 |
|---|---|
| Iupac Chemical Name | N-Methyl-N-[(1s,3s)-3-methyl-3-[[6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl]oxy]cyclobutyl]prop-2-enamide |
| Synonyms | BIIB-129 ; BIIB 129 ; BIIB129 |
| Molecular Formula | C19H22N6O2 |
| Molecular Weight | 366.42 |
| Smile | C=CC(N(C)[C@H]1C[C@](OC2=NC(C3=CN(C)N=C3)=CN4C2=CC=N4)(C)C1)=O |
| InChiKey | WBFSPPPOPIJCLF-DHFPXDALSA-N |
| InChi | InChI=1S/C19H22N6O2/c1-5-17(26)24(4)14-8-19(2,9-14)27-18-16-6-7-20-25(16)12-15(22-18)13-10-21-23(3)11-13/h5-7,10-12,14H,1,8-9H2,2-4H3/t14-,19+ |
| CAS Number | 2770960-52-4 |
| Related CAS | 2770960-52-4 |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |