Bexobrutideg ( NX-5948 )
Catalog No: 25197
CAS Number: 2649400-34-8
Purity: ≧98.0%
Bexobrutideg (NX-5948) is a BTK degrader.
For research use only. We do not sell to patients.
Chemical Information
| Name | Bexobrutideg ( NX-5948 ) |
|---|---|
| Iupac Chemical Name | 3-[4-(1-[[1-(6-[[(3S)-2,6-Dioxopiperidin-3-yl]carbamoyl]pyridin-3-yl)piperidin-4-yl]methyl]piperidin-4-yl)anilino]-5-[(3R)-3-(3-methyl-2-oxoimidazolidin-1-yl)piperidin-1-yl]pyrazine-2-carboxamide |
| Synonyms | Bexobrutideg ; NX-5948 ; NX 5948 ; NX5948 |
| Molecular Formula | C42H54N12O5 |
| Molecular Weight | 806.97 |
| Smile | O=C(C1=NC=C(N2C[C@H](N3CCN(C)C3=O)CCC2)N=C1NC4=CC=C(C5CCN(CC6CCN(C7=CC=C(C(N[C@@H](CC8)C(NC8=O)=O)=O)N=C7)CC6)CC5)C=C4)N |
| InChiKey | HPTPDBYCFHFWJG-CWTKIQHKSA-N |
| InChi | InChI=1S/C42H54N12O5/c1-50-21-22-54(42(50)59)32-3-2-16-53(26-32)35-24-45-37(38(43)56)39(48-35)46-30-6-4-28(5-7-30)29-14-17-51(18-15-29)25-27-12-19-52(20-13-27)31-8-9-33(44-23-31)40(57)47-34-10-11-36(55)49-41(34)58/h4-9,23-24,27,29,32,34H,2-3,10-22,25-26H2,1H3,(H2,43,56)(H,46,48)(H,47,57)(H,49,55,58)/t32-,34+/m1/s1 |
| CAS Number | 2649400-34-8 |
| Related CAS | 2649400-34-8 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
Coming soon.
| Targets | BTK degrader |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
