Bezuclastinib is an oral, small-molecule inhibitor of the kinase activity of the KIT D816V mutant, as well as that of other KIT exon 17 mutants.
For research use only. We do not sell to patients.
| Name | Bezuclastinib |
|---|---|
| Iupac Chemical Name | 4,5-Dimethyl-N-(2-phenyl-1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazole-3-carboxamide |
| Synonyms | Bezuclastinib ; CGT9486 ; PLX 9486 ; CGT 9486; PLX9486 ; CGT-9486; PLX-9486 |
| Molecular Formula | C19H17N5O |
| Molecular Weight | 331.38 |
| Smile | O=C(C1=NNC(C)=C1C)NC2=CN=C(NC(C3=CC=CC=C3)=C4)C4=C2 |
| InChiKey | NVSHVYGIYPBTEZ-UHFFFAOYSA-N |
| InChi | InChI=1S/C19H17N5O/c1-11-12(2)23-24-17(11)19(25)21-15-8-14-9-16(22-18(14)20-10-15)13-6-4-3-5-7-13/h3-10H,1-2H3,(H,20,22)(H,21,25)(H,23,24) |
| CAS Number | 1616385-51-3 |
| Related CAS | 1616385-51-3 |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
| Targets | c-kit Inhibitor |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |