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MAPK
Membrane Transporter/Ion Channel
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
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NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
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Cas Index 1
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Cas Index 1
1431866-33-9 | WEHI-539
(Catalog# : 17101613)
WEHI-539 is a highly potent and selective BCL-XL inhibitor. The pro-survival BCL-2 fa
1354825-58-3 | WEHI-345
(Catalog# : 1781007)
WEHI-345 is a potent and selective RIPK2 inhibitor which shows NOD signalling events
1214265-58-3 | WZ4003
(Catalog# : 17030203)
WZ4003 is a selective inhibitors of the LKB1-tumour-suppressor-activated NUAK kinases
1243243-89-1 | Wnt-C59
(Catalog# : 16122846)
Wnt-C59 is a potent porcupine (PORCN) inhibitor. Wnt-C59 inhibits PORCN activity in v
1421227-52-2 | WS3
(Catalog# : 16122747)
WS3 is a cell proliferation inducer via modulation of Erb3 binding protein-1 (EBP1)
153437-55-9 | WHI-P180 hydrochloride
(Catalog# : 611927)
WHI-P180 hydrochloride is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0
1062159-35-6 | WAY-600
(Catalog# : 161009014)
WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 n
1062161-90-3 | WYE-687
(Catalog# : 1610912)
WYE-687 is a potent and ATP-competitive and selective inhibitor of mTOR with IC50 of
1144068-46-1 | WYE-125132
(Catalog# : 161009008)
WYE-132 inhibited mTORC1 and mTORC2 in diverse cancer models in vitro and in vivo. Im
1062169-56-5 | WYE-354
(Catalog# : 1610101)
WYE-354 is a potent cell-permeable inhibitor of mTOR (IC50 = 4.3 nM) which blocks sig
19545-26-7 | Wortmannin
(Catalog# : 160926005)
It has an in vitro inhibitory concentration (IC50) of around 5 nM, making it a more p
1213269-23-8 | WZ4002
(Catalog# : 52822)
WZ4002 is a novel, mutant-selective EGFR inhibitor for EGFR(L858R)/(T790M) with IC50
1123231-07-1 | WAY-262611
(Catalog# : 52726)
WAY-262611 is a wingless -Catenin agonist that increases bone formation rate; with EC
1421227-53-3 | WS6
(Catalog# : 52224)
WS6 is a novel small molecule that promotes cell proliferation in rodent and human p
152854-19-8 (tartrate) | Xanomeline tartrate
(Catalog# : 2112067)
Xanomeline (LY-246,708) is an orthosteric muscarinic acetylcholine receptor (mAChR) a
1208229-58-6 | XP-23829
(Catalog# : 192143)
XP-23829, also known as tepilamide fumarate, is a hydroxycarboxylic acid receptor 2 l
192939-46-1 | Ximelagatran
(Catalog# : 185282)
Ximelagatran is an anticoagulant that has been investigated extensively as a replacem
1234480-50-2 | XMD8-92
(Catalog# : 17030608)
XMD8-92 is a BMK1 inhibitor and a highly selective inhibitor of ERK5 activity. XMD8-9
1345098-78-3 | XMD16-5
(Catalog# : 17021312)
XMD16-5 is a novel tyrosine kinase nonreceptor 2(TNK2) inhibitor with IC50s of 16 n
1234480-46-6 | XMD8-87
(Catalog# : 17021311)
XMD8-87 is a novel tyrosine kinase nonreceptor 2(TNK2) inhibitor with IC50s of 38 n
1251156-08-7 | XL388
(Catalog# : 161009016)
XL388 inhibited cellular phosphorylation of mTOR complex 1 (p-p70S6K, pS6, and p-4E-B
1435488-37-1 | XMD17-109
(Catalog# : 16071410)
XMD17-109 is a novel, specific inhibitor of ERK-5 with an EC50 value of 4.2 M in HEK2
1624117-53-8 | XY1
(Catalog# : 021803)
XY1 is a very close analogue of SGC707 (a potent, selective, and non-competitive inhi
1365267-27-1 | X-396
(Catalog# : 011804)
X-396 is an orally available small molecule inhibitor of the receptor tyrosine kinase
1123889-87-1 | XL765
(Catalog# : 111910)
XL765 is a PI3K/mTOR dual kinase inhibitor with IC50 values of 157 nM, 39 nM, 113 nM,
1515856-92-4 | XEN445
(Catalog# : 52501)
XEN445 is a potent and selective EL inhibitor(IC50=0.237 uM), that showed good ADME a
1936529-65-5 | YKL-05-099
(Catalog# : 21241)
YKL-05-099 is a selective inhibitor of Salt-Inducible Kinase (SIK).
181147-28-4 | YCN47284
(Catalog# : 2073105)
YCN47284 is an aromatic guanylhydrazone compounds with antimalarial activity.
1312005-62-1 | YF-2 hydrochloride
(Catalog# : 193151)
YF-2 hydrochloride is a highly selective, blood-brain-barrier permeable histone acety
1364488-67-4 | YH239-EE
(Catalog# : 192213)
YH239-EE is a highly potent p53-MDM2 antagonist.
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
2377000-84-3 | Dencatistat
(Catalog# : 25177)
Dencatistat is an orally bioavailable, small molecule inhibitor of cytidine triphosph
1898207-64-1 | DS-1001b
(Catalog# : 25178)
DS-1001 is an oral brain-penetrant mutant IDH1 selective inhibitor.
1016340-64-9 | Z57346765
(Catalog# : 25191)
Z57346765 is a PGK1-specific inhibitor that reduces the activity of metabolic enzymes
2416095-06-0 | CBR-470-1
(Catalog# : 25192)
CBR-470-1 is an Inhibitor of the glycolytic enzyme PGK1that induces Nrf2 activity.
1898206-17-1 | Safusidenib
(Catalog# : 25149)
Safusidenib, also known as DS-1001, is an oral isocitrate dehydrogenase [NADP] cytopl
2803470-63-3 | HC-7366
(Catalog# : 25076)
HC-7366 is a potent and selective activator of the general control nonderepressible 2
146426-40-6 | Flavopiridol ( Alvocidib )
(Catalog# : 237071)
Alvocidib is a synthetic dihydroxyflavone that is 5,7-dihydroxyflavone which is subst
2201056-66-6 | AG-270
(Catalog# : 25176)
MAT2A Inhibitor AG-270 is an orally available small molecule inhibitor of methionine
618913-30-7 | AZD-5904
(Catalog# : 181121)
AZD5904 is a potent orally bioavailable MPO inhibitor. In preclinical studies, AZD590
2035010-37-6 | ALT-007
(Catalog# : 25157)
ALT-007 is an orally bioavailable SPT inhibitor that is more potent than myriocin, sa