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MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
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Protein Tyrosine Kinase
Proteases
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
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TGF-beta/Smad
Ubiquitin
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Cas Index 1
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Cas Index 1
173897-44-4 | Y-39983 HCl
(Catalog# : 17021305)
Y-39983 is a selective rho-associated protein kinase(ROCK) inhibitor with an IC50 o
1236188-16-1 | 740 Y-P (PDGFR 740Y-P)
(Catalog# : 17021302)
740 Y-P is cell-permeable phosphopeptide activator ofPI3K. The PDGFR 740Y-P peptide s
163769-88-8 | YM-90709
(Catalog# : 16122849)
YM-90709 is an interleukin-5 receptor antagonist. YM-90709 inhibits the binding of IL
129184-48-1 | Y-29794 Tosylate
(Catalog# : 16122848)
Y-29794 Tosylate is an orally active, potent and specific non-peptide prolyl endopept
1346753-00-1 | YHO-13351
(Catalog# : 6111512)
YHO-13351 is the water-soluble prodrug of YHO-13177, which is a potent and specific i
1273323-67-3 | YLF-466D
(Catalog# : 611813)
YLF-466D is an allosteric AMPK activator.YLF466D activated recombinant human 111, 211
146986-50-7 | Y27632(free base)
(Catalog# : 16070918)
Y27632 is a selective ROCK inhibitor, which inhibits ET-1-induced increases in natriu
1370003-76-1 | YK11
(Catalog# : 030910)
Coming soon!
129830-38-2 | Y-27632 dihydrochloride
(Catalog# : 010421)
Y-27632 2Hcl is a selective ROCK1 (p160ROCK) inhibitor with Ki of 140 nM, exhibits &g
1016340-64-9 | Z57346765
(Catalog# : 25191)
Z57346765 is a PGK1-specific inhibitor that reduces the activity of metabolic enzymes
167354-41-8 | Zosuquidar ( LY-335979 )
(Catalog# : 25127)
Zosuquidar is a potent modulator of P-glycoprotein-mediated multi-drug resistance.
1640282-42-3 | Zunsemetinib
(Catalog# : 24012)
Zunsemetinib is an investigational oral mitogen-activated protein kinase-activated pr
1606974-33-7 | Zatolmilast
(Catalog# : 20651)
Zatolmilast is a phosphodiesterase IV inhibitor.
1851412-93-5 | Zavondemstat
(Catalog# : 20610)
Zavondemstat is a KDM4 inhibitor with potential as an antineoplastic agent.
1438280-73-9 | 1Z105
(Catalog# : 20567)
1Z105 is a TLR4/MD2 ligand, significantly reducing the IL-6 secretion by subsequent c
1211825-25-0 | ZINC40099027 (ZN27)
(Catalog# : 20513)
ZINC40099027 (ZN27) is a specific focal adhesion kinase (FAK) activator that promotes
1661854-97-2 | Zipalertinib
(Catalog# : 20317)
Zipalertinib, also known as TAS6417, CLN-081, is a Novel EGFR Inhibitor Targeting Exo
1713240-67-5 | Zegocractin ( CM-4620 )
(Catalog# : 204504)
Zegocractin (CM-4620, Auxora(TM)) is a small-molecule inhibitor of the calcium releas
1080028-80-3 | Zamicastat
(Catalog# : 189271)
Zamicastat is a potent and selective dopamine β-mono-oxygenase inhibitor.
101975-10-4 | Zardaverine
(Catalog# : 185186)
Zardaverine is a Phosphodiesterase 3/4 inhibitor.
1691249-45-2 | Zanubrutinib
(Catalog# : 18577)
Zanubrutinib, aslo known as BGB-3111, is a potent and highly selective small molecule
139180-30-6 | ZM241385
(Catalog# : 17022714)
ZM241385 is an adenosine A2A-receptor antagonist. ZM241385 enhances neuronal survival
1181226-02-7 | ZL006
(Catalog# : 16122851)
ZL006 is a PSD95-nNOS protein-protein interaction inhibitor. ZL006 (EC50: 12.88 M) di
1780259-94-0 | ZK-756326 dihydrochloride
(Catalog# : 16122850)
ZK-756326 is a potent, selective and non-peptide CCR8 chemokine receptor agonist. ZK
1883548-91-1 | ZLN024 hydrochloride
(Catalog# : 611814)
ZLN024 Hcl is a novel AMPK allosteric activator; activated 111 and 211 by around 2C2.
161401-82-7 | Z-Vad-fmk, non-methylated
(Catalog# : 16071403)
Z-Vad-fmk, non-methylated
105637-38-5 | Z-FA-FMK
(Catalog# : 16062111)
Z-FA-FMK
186497-07-4 | Zibotentan
(Catalog# : 011908)
Zibotentan is an orally available selective antagonist of the endothelin-A (ET-A) rec
193000-39-4 | ZM323881 hydrochloride
(Catalog# : 111008)
ZZZM 323881 Hcl is a potent and selective VEGFR2 inhibitor with IC50 of <2 nM, alm
187389-52-2 | Z-VAD-FMK
(Catalog# : 110604)
Z-VAD-FMK is a cell-permeable, irreversible broad-spectrum caspase inhibitor, blocks
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
85622-93-1 | Temozolomide
(Catalog# : 25209)
Temozolomide is an alkylating agent.
2035010-37-6 | ALT-007
(Catalog# : 25157)
ALT-007 is an orally bioavailable SPT inhibitor that is more potent than myriocin, sa
2376397-93-0 | Opakalim
(Catalog# : 25193)
Opakalim (BHV-7000) is an oral, small-molecule activator of Kv7.2/7.3 potassium chann
2102501-84-6 | PF-06835919 ( MDK-1846 )
(Catalog# : 193264)
MDK1846 is a potent ketohexokinase (KHK) inhibitor.
2271348-04-8 | MK256
(Catalog# : 25208)
MK256 is a novel CDK8 inhibitor with potent antitumor activity in AML through downreg
2351225-46-0 | NSD1 inhibitor BT5
(Catalog# : 25207)
BT5 potently inhibits NSD1, engages the SET domain in cells, and reduces H3K36me2 lev
1049704-18-8 | MA242 TFA
(Catalog# : 25206)
MA242 isMDM2 and NFAT1 dual inhibitorthat induces MDM2 auto-ubiquitination and degrad
2800223-30-5 | Dabogratinib ( TYRA-300 )
(Catalog# : 24073)
Dabogratinib ( TYRA-300 ) is an Oral Selective FGFR3 Inhibitor (IC50 = 11 nM) for the
N/A | AF710B
(Catalog# : 25205)
AF710B is a highly selective and potent allosteric agonist for M1 muscarinic and σ1
2957874-18-7 | MAT2A inhibitor 5
(Catalog# : 25204)
MAT2A inhibitor 5 has a high potency for inhibiting MAT2A and a remarkable selectivit