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WYE-354

Catalog No.: 1610101
Cas No.: 1062169-56-5
Purity : 98% by HPLC 
1610101 - WYE-354 | CAS 1062169-56-5

Catalog number : 1610101

CAS number : 1062169-56-5

Molecular Formula : C24H29N7O5 

Molecular Weight : 495.53 

Iupac Chemical Name : methyl 4-(6-(4-((methoxycarbonyl)amino)phenyl)-4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate 

Smile : COC(=O)NC1=CC=C(C=C1)C1=NC(=C2C(=N1)N(N=C2)C2CCN(CC2)C(=O)OC)N2CCOCC2

InChiKey : IMXHGCRIEAKIBU-UHFFFAOYSA-N

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SynonymsWYE354; WYE-354; WYE 354 
Molecular FormulaC24H29N7O5 
Molecular Weight495.53 
AppearanceSolid powder 
Purity98% by HPLC 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
SmileCOC(=O)NC1=CC=C(C=C1)C1=NC(=C2C(=N1)N(N=C2)C2CCN(CC2)C(=O)OC)N2CCOCC2
InChiKeyIMXHGCRIEAKIBU-UHFFFAOYSA-N
InChiInChI=1S/C24H29N7O5/c1-34-23(32)26-17-5-3-16(4-6-17)20-27-21(29-11-13-36-14-12-29)19-15-25-31(22(19)28-20)18-7-9-30(10-8-18)24(33)35-2/h3-6,15,18H,7-14H2,1-2H3,(H,26,32)
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WYE-354 is a potent cell-permeable inhibitor of mTOR (IC50 = 4.3 nM) which blocks signaling through both mTOR complex 1 (mTORC1) and mTORC2.

 

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