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WEHI-539

Catalog No.: 17101613
Cas No.: 1431866-33-9
Purity : >98%
17101613 - WEHI-539 | CAS 1431866-33-9

Catalog number : 17101613

CAS number : 1431866-33-9

Molecular Formula : C31H29N5O3S2

Molecular Weight : 583.72

Chemical Name : WEHI-539

Smile : O=C(C1=C(CCCOC2=CC=C(CN)C=C2)SC(C(C=C/34)=CC=C4CCCC3=N/NC5=NC6=CC=CC=C6S5)=N1)O

InChiKey : JKMWZKPAXZBYEH-JWHWKPFMSA-N

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SynonymsWEHI-539; WEHI 539; WEHI539
Molecular FormulaC31H29N5O3S2
Molecular Weight583.72
Appearanceoff-white solid
Purity>98%
SolubilitySoluble in DMSO, not in water
Storage3 years -20ºCpowder
Shipping ConditionShipped under ambient temperature
SmileO=C(C1=C(CCCOC2=CC=C(CN)C=C2)SC(C(C=C/34)=CC=C4CCCC3=N/NC5=NC6=CC=CC=C6S5)=N1)O
InChiKeyJKMWZKPAXZBYEH-JWHWKPFMSA-N
InChiInChI=1S/C31H29N5O3S2/c32-18-19-10-14-22(15-11-19)39-16-4-9-27-28(30(37)38)34-29(40-27)21-13-12-20-5-3-7-24(23(20)17-21)35-36-31-33-25-6-1-2-8-26(25)41-31/h1-2,6,8,10-15,17H,3-5,7,9,16,18,32H2,(H,33,36)(H,37,38)/b35-24+
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WEHI-539 is a highly potent and selective BCL-XL inhibitor. The pro-survival BCL-2 family protein BCL-XL is often overexpressed in solid tumors and renders malignant tumor cells resistant to anticancer therapeutics.

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