XMD16-5 is a novel tyrosine kinase nonreceptor 2(TNK2) inhibitor with IC50s of 16 nmol/L and 77 nmol/L for the D163E and R806Q mutations.
XMD16-5 is found to be potent in the inhibition of TNK2 phosphorylation. XMD8-87 and XMD16-5 potently inhibit phosphorylation of TNK2 truncation mutations found in solid tumor types.
For research use only. We do not sell to patients.
| Name | XMD16-5 |
|---|---|
| Iupac Chemical Name | XMD16-5 |
| Synonyms | N/A |
| Molecular Formula | C23H24N6O2 |
| Molecular Weight | 416.48 |
| InChiKey | |
| InChi | |
| CAS Number | 1345098-78-3 |
| Related CAS |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
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| Targets | |
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| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |