Catalog number : 17021312
CAS number : 1345098-78-3
Molecular Formula : C23H24N6O2
Molecular Weight : 416.48
Iupac Chemical Name : XMD16-5
XMD16-5 is a novel tyrosine kinase nonreceptor 2(TNK2) inhibitor with IC50s of 16 nmol/L and 77 nmol/L for the D163E and R806Q mutations.
XMD16-5 is found to be potent in the inhibition of TNK2 phosphorylation. XMD8-87 and XMD16-5 potently inhibit phosphorylation of TNK2 truncation mutations found in solid tumor types.
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