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XEN445

Catalog No.: 52501
Cas No.: 1515856-92-4
Purity : 98% 

XEN445 is a potent and selective EL inhibitor(IC50=0.237 uM), that showed good ADME and PK properties, and demonstrated in vivo efficacy in raising plasma HDLc concentrations in mice 

For research use only. We do not sell to patients.

Chemical Information

NameXEN445
Iupac Chemical Name(S)-2-(3-(pyridin-2-ylmethoxy)pyrrolidin-1-yl)-5-(trifluoromethyl)benzoic acid 
Molecular FormulaC18H17F3N2O3 
Molecular Weight366.33 
SmileO=C(O)C1=CC(C(F)(F)F)=CC=C1N2C[C@@H](OCC3=NC=CC=C3)CC2
InChiKeyNBGRERFNOKZQLO-AWEZNQCLSA-N
InChiInChI=1S/C18H17F3N2O3/c19-18(20,21)12-4-5-16(15(9-12)17(24)25)23-8-6-14(10-23)26-11-13-3-1-2-7-22-13/h1-5,7,9,14H,6,8,10-11H2,(H,24,25)/t14-/m0/s1
CAS Number1515856-92-4
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Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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Formulationoff-white solid 
Purity98% 
Storage3 years -20ºCpowder 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

52501 - XEN445 | CAS 1515856-92-4

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