武汉永璨生物科技有限公司
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抑制剂/受体激动剂
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PROTAC
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分子砌块
Aldehydes
Amines
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Boronic Acids
Bromides
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Deuterated
Fluorides
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Indoles and Oxindoles
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Pyrimidines
Quinolines
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联系我们
公司简介
联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
Microbiology
Others
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
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产品名字索引 J
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产品名字索引 J
JNJ-42165279
(Catalog# : 16123025, Cas# :
1346528-50-4
)
JNJ-42165279 is a potent and selective fatty acid amide hydrolase (FAAH) inhibitor. J
JI-101
(Catalog# : 16122823, Cas# :
900573-88-8
)
JI-101 is an orally active inhibitor of vascular endothelial growth factor receptor 2
JPH203(KYT-0353)
(Catalog# : 6112701, Cas# :
1037592-40-7
)
JPH203(also known as KYT-0353) is a potent and selective LAT1 selective ( L-type amin
JAK3-IN-1
(Catalog# : 6111506, Cas# :
1805787-93-2
)
JAK3-IN-1 is a potent JAK3 inhibitor with IC50 of 4.8 nM, also inhibits JAK1 (IC50 =
JWH-133
(Catalog# : 6111109, Cas# :
259869-55-1
)
JWH 133 is a potent CB2 selective agonist with Ki of 3.4 nM, 200-fold selective over
(+)-JQ1
(Catalog# : 16070105, Cas# :
1268524-70-4
)
(+)-JQ1 is a BET potent BET bromodomain Inhibitor. Bromodomain and extra terminal dom
JNJ-42041935
(Catalog# : 031401, Cas# :
1193383-09-3
)
JNJ-42041935 is a potent (pKi = 7.3-7.9), 2-oxoglutarate competitive, reversible, and
JH-VIII-157-02
(Catalog# : 62103, Cas# :
1639422-97-1
)
JH-VIII-157-02, a structural analogue of alectinib, is potent against the G1202R muta
JH-II-127
(Catalog# : 012010, Cas# :
1700693-08-8
)
JH-II-127 is a potent and selective inhibitor of both wild-type and G2019S mutant LRR
JNJ 40411813
(Catalog# : 122939, Cas# :
1127498-03-6
)
JNJ-40411813 is a novel positive allosteric modulator of the metabotropic Glutamate 2
JNJ 303
(Catalog# : 122938, Cas# :
878489-28-2
)
Coming soon!
JZL195
(Catalog# : 111007, Cas# :
1210004-12-8
)
JZL195 is a selective and efficacious dual FAAH/MAGL inhibitor with IC50 of 13 nM and
JNJ-31020028
(Catalog# : 100903, Cas# :
1094873-14-9
)
JNJ-31020028 is a selective brain penetrant small molecule antagonist of the neuropep
JSH-23
(Catalog# : 52729, Cas# :
749886-87-1
)
JSH-23 is an inhibitor of NF-B transcriptional activity with IC50 of 7.1 M.
JNJ-26854165 (Serdemetan)
(Catalog# : 52522, Cas# :
881202-45-5
)
JNJ-26854165 (Serdemetan) acts as a HDM2 ubiquitin ligase antagonist and also induces
J-147
(Catalog# : 52505, Cas# :
1146963-51-0
)
J-147 is a broad spectrum neuroprotective phenyl hydrazide compound(EC50=60-115 nM) w
JANEX-1
(Catalog# : 52220, Cas# :
202475-60-3
)
Janex-1 is a cell-permeable, reversible, potent, ATP-competitive, and specific inhibi
JIB-04
(Catalog# : 52225, Cas# :
199596-05-9
)
JIB-04 is a pan-selective Jumonji histone demethylase inihibitor with IC50 of 230, 34
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产品分类
信号通路
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
----
NEKs
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
----
GLP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
----
Lactate dehydrogenase
----
Glyoxalase (GLO)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
CT1812 ( Zervimesine )
(Catalog# : 193283, Cas# :
1802632-22-9
)
CT-1812是一种同类首创的、可口服的sigma-2/PGRMC1拮抗剂(αβ寡聚体
BLU-808
(Catalog# : 26A024, Cas# :
3041025-10-6
)
BLU-808是一种针对肥大细胞疾病的野生型c-KIT的强效且具有选择性的
Zedoresertib
(Catalog# : 26A023, Cas# :
2243882-74-6
)
Zedoresertib(Debio 0123)是一种脑渗透剂,高选择性WEE1激酶抑制剂。
BEN-28010
(Catalog# : 26A022, Cas# :
3033961-38-2
)
BEN-28010是一种自由脑渗透剂,强效且具有选择性的CHK1抑制剂。
4-((2-(甲氨基)-6-(2,2,2-三氟乙基)噻吩并[2,3-d]嘧啶-4-基)氨基)哌啶-1-甲酸叔丁酯
(Catalog# : 26B007, Cas# :
3107291-07-3
)
Muvalaplin
(Catalog# : 20528, Cas# :
2565656-70-2
)
Muvalaplin是一种小分子,通过干扰载脂蛋白(a)与载脂蛋白B100的结合
MAT2A-IN-22
(Catalog# : 26A021, Cas# :
2925330-18-1
)
MAT2A-IN-22 (Compound 29-1) 是一种可透过血脑屏障的和口服有效的 MAT2A
AD-8007
(Catalog# : 26A018, Cas# :
1497439-74-3
)
AD-8007是一种选择性且可穿透血脑屏障的乙酰辅酶A合成酶2(ACSS2)
ZY-444
(Catalog# : 26A020, Cas# :
1802650-31-2
)
ZY-444是一种通过抑制PC活性发挥抗癌作用的药物。
AD-5584
(Catalog# : 26A019, Cas# :
2306525-79-9
)
AD-5584是一种新型脑渗透性ACSS2抑制剂。