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+86-17702719238
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抑制剂/受体激动剂
Angiogenesis
Anti-infection
Apoptosis
Autophagy
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DNA Damage
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Cas号索引 1
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Cas号索引 1
1190307-88-0 | PSI-7977
(Catalog# : 52718)
PSI-7977(sofosbuvir) is an investigational nucleotide analog for treatment of chronic
1092364-38-9 | Poziotinib
(Catalog# : 52634)
Poziotinib(NOV120101; HM781-36B) is an irreversible Pan-HER inhibitor with IC50s of 3
1255517-76-0 | PF-4708671
(Catalog# : 52631)
PF-4708671 is a novel cell-permeable inhibitor of S6K1 (p70 ribosomal S6 kinase 1), w
157716-52-4 | Perifosine
(Catalog# : 52613)
Perifosine (KRX-0401; D-21266; NSC 639966) is a novel Akt inhibitor with IC50 of 4.7
1191951-57-1 | PHT-427
(Catalog# : 52583)
PHT-427 is a dual Akt and PDPK1 inhibitor (high affinity binding for the PH domains o
1349796-36-6 | PI3K-IN-1
(Catalog# : 52560)
PI3K-IN-1 is a potent inhibitor of PI3K, more information can be found in patent WO20
152121-53-4 | PD 169316
(Catalog# : 52513)
PD 169316 is a potent, cell-permeable and selective p38 MAP kinase inhibitor (IC50 =
153436-54-5 | PD153035
(Catalog# : 52223)
PD153035(ZM 252868; AG 1517) is a potent and specific inhibitor of EGFR with Ki and I
1627676-59-8 | PFI-2
(Catalog# : 52113)
PFI-2 is a potent, selective, and cell-activelysine methyltransferase SETD7inhibitor
1454846-35-5 | PF-06463922
(Catalog# : 51701)
PF-06463922 is an orally available, ATP-competitive inhibitor of the receptor tyrosin
1802735-28-9 | QBS10072S
(Catalog# : 25190)
QBS10072S 是一种血脑屏障 (BBB) 渗透剂,由细胞毒性化疗结构域 N-双
150323-78-7 | Quipazine dimaleate
(Catalog# : 20462)
Quipazine dimaleate is a selective 5-HT3 receptor agonist that also displays antagoni
1893397-65-3 | QUN97653
(Catalog# : 204507)
QUN97653, also known as TBK1/IKKε-IN-5, is a dual TBK1 and IKKε inhibitor, with IC5
1334719-95-7 | Q-203
(Catalog# : 17106003)
Q-203是一种有效的、具有选择性的新药。
1135695-98-5 | Q-VD-OPH
(Catalog# : 16071010)
Q-VD-OPH is a selective, brain and cell permeable, highly potent and irreversible inh
144875-48-9 | Qesiquimod
(Catalog# : 120814)
Qesiquimod is a potent synthetic agonist of TLR7/TLR8 that possesses antiviral and an
1443361-20-3 | 3-Quinolinecarboxylic acid, 1,4-dihydro-8- methoxy-1-[(4-methoxyphenyl)methyl]-4-oxo-, ethyl ester
(Catalog# : 102902)
Coming soon!
1237744-13-6 | QNZ46
(Catalog# : 91006)
QNZ46 is a noncompetitive and voltage-independent antagonist selective for NR2C/D con
1039760-91-2 , 2074613-88-8 [ALTERNATIVE] | Rosolutamide ( AJ-201 ; ASC-JM17 )
(Catalog# : 25196)
Rosolutamide (formerly known as AJ-201, ASC-JM-17 or ALZ-002) 是一种姜黄素类似
1575596-29-0 | Rilzabrutinib
(Catalog# : 25106)
Rilzabrutinib, also known as PRN1008, is a reversible covalent, selective and oral ac
195514-63-7 | Rimiducid
(Catalog# : 25100)
Rimiducid, also known as AP1903, is a lipid-permeable bivalent "dimerizer"
1575591-66-0 | Rilzabrutinib ( PRN1008 )
(Catalog# : 25091)
Rilzabrutinib ( PRN1008 ) 是一种口服、可逆、共价的布鲁顿酪氨酸激酶
1305267-37-1 | Roginolisib
(Catalog# : 25068)
Roginolisib, also known as MSC2360844 and IOA-244, is a potent, orally active and sel
1496510-51-0 | Relacorilant
(Catalog# : 25035)
Relacorilant is discontinued.
1235733-73-9 | (Rac)-AF710B
(Catalog# : 24083)
AF-710B 是 σ 和 M1 毒蕈碱受体的激动剂;AF710B 是 AF710 的对映体。
1494684-33-1 | Risovalisib mesylate
(Catalog# : 24078)
CYH33 (CYH-33) is a novel potent, PI3Kα-selective inhibitor with IC50 of 5.9 nM/598
1423719-27-0 | (R,S)-BI 1015550
(Catalog# : 230403)
BI 1015550 is a novel PDE4 inhibitor showing a preferential enzymatic inhibition of P
139339-45-0 | Ro 24-7429
(Catalog# : 2320201)
Ro24-7429是一种有效的口服活性HIV-1 反式激活蛋白Tat 拮抗剂和一种
1239729-06-6 | 布瑞拉沙秦(Brilaroxazine)
(Catalog# : 822224)
RP-5063(Brilaroxazine) 是一种多模式的血清素和多巴胺受体调节剂,
1859053-21-6 | Rucaparib Camsylate
(Catalog# : 20316)
Rucaparib camsylate is a potent, orally available inhibitor of poly ADP-ribose polyme
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产品分类
信号通路
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
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----
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----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
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----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
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Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
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Iodos
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--
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--
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--
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--
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--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
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On Sale
新产品
天然化合物
最新产品
85622-93-1 | Temozolomide
(Catalog# : 25209)
替莫唑胺是一种烷化剂。
2035010-37-6 | ALT-007
(Catalog# : 25157)
ALT-007 是一种口服生物可利用的 SPT 抑制剂,比多球菌素更有效,
2376397-93-0 | Opakalim
(Catalog# : 25193)
Opakalim(BHV-7000)是Kv7.2/7.3钾通道(KCNQ2/3)的口服小分子激活剂,
2102501-84-6 | PF-06835919 ( MDK-1846 )
(Catalog# : 193264)
MDK1846是一种强效的酮己糖激酶(KHK)抑制剂。
2271348-04-8 | MK256
(Catalog# : 25208)
MK256是一种新型CDK8抑制剂,通过下调STAT通路在急性髓系白血病(
2351225-46-0 | NSD1 抑制剂 BT5
(Catalog# : 25207)
BT5可有效抑制NSD1,与细胞中的SET结构域结合,并降低H3K36me2水平。
1049704-18-8 | MA242 TFA
(Catalog# : 25206)
MA242是一种MDM2和NFAT1双重抑制剂,可诱导MDM2自泛素化及降解,并抑
2800223-30-5 | Dabogratinib ( TYRA-300 )
(Catalog# : 24073)
Dabogratinib ( TYRA-300 )是一种口服选择性成纤维细胞生长因子受体3(
N/A | AF710B
(Catalog# : 25205)
AF710B 是一种高效、选择性变构 M1 毒蕈碱和 σ1 受体激动剂。 AF710
2957874-18-7 | MAT2A inhibitor 5
(Catalog# : 25204)
MAT2A抑制剂5具有抑制MAT2A的高效力和对MTAP缺失的癌症细胞系的显著