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+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
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Membrane Transporter/Ion Channel
others
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Amines
Amino Acids
Anilines
Boronic Acids
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Deuterated
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Cas号索引 1
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Cas号索引 1
1995889-48-9 | Parsaclisib HCl
(Catalog# : L20333)
Parsaclisib, also known as INCB050465, is a novel PI3Kδ inhibitor which synergizes w
1426698-88-5 | Parsaclisib free base
(Catalog# : L20332)
Parsaclisib, also known as INCB050465, is a novel PI3Kδ inhibitor which synergizes w
1221962-86-2 | PS210
(Catalog# : 20282)
PS210 is a substrate-selective inhibitor of protein kinase PDK1. It acts by binding t
171744-42-6 | PD-159206
(Catalog# : 20278)
PD-159206 is a nucleocapsid inhibitor. It exhibits good antiviral activity against HI
18550-98-6 | 3PO
(Catalog# : 21227)
3PO is a PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase) inhibitor. 3PO
1034189-82-6 | PF-06802861 ( ARRY 371797 ; ARRY-797 )
(Catalog# : 2073108)
ARRY 797(也称为ARRY 371797或PF 06802861)是一种具有口服活性,选择性
1917294-46-2 | PF-04745637
(Catalog# : 2071623)
PF-04745637 is a TRPV1 antagonist.
1629869-44-8 | Pimodivir ( VX-787 )
(Catalog# : 2071401)
Pimodivir (VX-787) 是一种可口服的甲型流感病毒聚合酶抑制剂,通过
1454619-14-7 | PU-WS13
(Catalog# : 206701)
PU-WS13 is a potent, Grp94-specific Hsp90 inhibitor of the purine scaffold class. PU-
1953130-87-4 | PTI-428(PTI428)
(Catalog# : 31619)
PTI-428是一种研究性CFTR放大器,开发用于治疗CFTR基因中发生F508del
1415637-72-7 | PF-05085727
(Catalog# : 1932011)
PF-05085727是一种强效、选择性和脑穿透性磷酸二酯酶2A抑制剂。
1252637-35-6 | Petesicatib
(Catalog# : 193206)
Petesicatib是一种组织蛋白酶抑制剂的候选药物。
187235-37-6 | Pretomanid
(Catalog# : 193110)
Pretomanid,也被称为PA-824,一种生物还原药物。PA-824具有较强的体
1341224-83-6 | PF-4136309
(Catalog# : 192282)
PF-4136309,又称INCB8761,是一种口服的人趋化因子受体2 (CCR2)拮抗剂
1078166-57-0 | PF04418948
(Catalog# : 191141)
PF-04418948是一种新型高效选择性前列腺素EP2受体拮抗剂。
1352879-65-2 | PF74
(Catalog# : 1812253)
PF-3450074,又称PF74,是一种针对HIV衣壳蛋白的HIV-1抑制剂。PF74与HI
1672665-49-4 | PT2385
(Catalog# : 1812135)
PT2385是一种口服活性小分子缺氧诱导因子(HIF)-2alpha抑制剂,具有潜
133413-70-4 | PF 1022A
(Catalog# : 1811232)
PF1022A是一种新型的驱虫药,与嗜乳激素样跨膜受体结合,对线虫
146464-95-1 | 普拉曲沙
(Catalog# : 1811221)
普拉曲沙是二氢叶酸还原酶(DHFR)的一种叶酸模拟抑制剂,对叶酸还
1037589-69-7 | PF-05231023
(Catalog# : 1811162)
PF-05231023是一种长效FGF21仿生产品。PF-05231023可以减轻非人类灵长类
1311174-68-1 | PH-002
(Catalog# : 1810234)
PH-002是一种新型的载脂蛋白(apo) E4分子内区域相互作用的神经细胞
1513857-77-6 | Pemigatinib (INCB054828)
(Catalog# : 1810164)
Pemigatinib是一种酪氨酸激酶抑制剂,也是一种抗肿瘤药物候选药物
1022899-36-0 | PCI-33380
(Catalog# : 18943)
PCI-33380是基于ibrutinib支架设计的,已被用于细胞和体内研究,证实
1613373-33-3 | PCO371
(Catalog# : 187125)
PCO371是一种有效的、选择性的PTHR1激动剂,用于治疗低甲状旁腺功
1927857-61-1 | PQR530
(Catalog# : 18756)
PQR530是一种高效的日常pan-PI3K/mTORC1/2抑制剂。
1269662-73-8 | Pyrotinib
(Catalog# : 18731)
Pyrotinib,又称SHR -1258,是一种口服生物利用的双激酶抑制剂,是表
1268244-85-4 | PX20606反式消旋体
(Catalog# : 186274)
PX20606, 也称为PX-102, 是一种FXR激动剂。
1394033-54-5 | PF-05180999
(Catalog# : 186153)
PF-05180999是一个强有力的和选择性PDE2a抑制剂(PDE2a的IC50 = 0.001μM,
1428333-96-3 | Pritelivir甲磺酸盐
(Catalog# : 186152)
Pritelivir,又名AIC-316和BAY 57-1293,是一种有效的螺旋酶抑制剂。
1446261-44-4 | Pamiparib
(Catalog# : 185233)
Pamiparib是高选择性PARP-1/2抑制剂。临床试验中表现出良好的抗肿瘤
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
--
Antibody-drug Conjugate/ADC Related
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
2102501-84-6 | PF-06835919 ( MDK-1846 )
(Catalog# : 193264)
MDK1846是一种强效的酮己糖激酶(KHK)抑制剂。
2671128-05-3 | FHD-286
(Catalog# : 20471)
FHD-286 is an oral, small-molecule, selective, allosteric inhibitor of BRG1 and BRM i
3002056-30-3 | NST-628
(Catalog# : 24058)
NST-628 是具有血脑屏障渗透性的 MAPK 通路分子胶,能够抑制 RAF 磷
2893778-31-7 | PHGDH-IN-3
(Catalog# : 25077)
PHGDH-IN-3 is an orally active phosphoglycerate dehydrogenase (PHGDH) inhibitor.
2882165-79-7 | CFT1946
(Catalog# : 25078)
CFT1946 是一种口服生物可利用的小分子降解剂,可降解实体瘤中的
68238-36-8 | 异硫蓝
(Catalog# : 178017)
Isosulfan blue 是一种用于淋巴管造影中淋巴管识别的蓝色染料。Isos
2803470-63-3 | HC-7366
(Catalog# : 25076)
HC-7366 is a potent and selective activator of the general control nonderepressible 2
2226636-04-8 | Soquelitinib ( CPI-818 )
(Catalog# : 20671)
Soquelitinib(CPI-818)是一种高度选择性的共价白细胞介素-2诱导的T
2230263-60-0 | Crelosidenib
(Catalog# : 24101)
Crelosidenib is an isocitrate dehydrogenase 1 (IDH1) inhibitor. It is an antineoplast
1260247-42-4 | LLL12
(Catalog# : 25075)
LLL12 is a potent STAT3 inhibitor. LLL12 inhibits colony formation and cell migration