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QNZ46

Catalog No.: 91006
Cas No.: 1237744-13-6
Purity : 98% 
91006 - QNZ46 | CAS 1237744-13-6

Catalog number : 91006

CAS number : 1237744-13-6

分子式 : C24H17N3O6 

分子量 : 443.408 

Iupac 化学名称 : 4-[6-Methoxy-2-[(1E)-2-(3-nitrophenyl)ethenyl]-4-oxo-3(4H)-quinazolinyl]-benzoic Acid 

Smile : COC=1C=C2C(N(C(=NC2=CC1)\C=C\C1=CC(=CC=C1)[N+](=O)[O-])C1=CC=C(C(=O)O)C=C1)=O

InChiKey : GNLVJIICVWDSNI-LFYBBSHMSA-N

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同义词QNZ-46 
英文同义词QNZ-46 
分子式C24H17N3O6 
分子量443.408 
外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileCOC=1C=C2C(N(C(=NC2=CC1)\C=C\C1=CC(=CC=C1)[N+](=O)[O-])C1=CC=C(C(=O)O)C=C1)=O
InChiKeyGNLVJIICVWDSNI-LFYBBSHMSA-N
InChiInChI=1S/C24H17N3O6/c1-33-19-10-11-21-20(14-19)23(28)26(17-8-6-16(7-9-17)24(29)30)22(25-21)12-5-15-3-2-4-18(13-15)27(31)32/h2-14H,1H3,(H,29,30)/b12-5+
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QNZ46 is a noncompetitive and voltage-independent antagonist selective for NR2C/D containing NMDA receptors (IC50 = 6, 3, 229, and >300 M for NR2C, NR2D, NR2A, and NR2B, respectively). Inhibition on NR2C/D containing NMDA receptors is glutamate-binding, but not glycine-binding, dependent.
 

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