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Q-VD-OPH

编号: 16071010
Cas号: 1135695-98-5
纯度: 98% by HPLC 

Q-VD-OPH is a selective, brain and cell permeable, highly potent and irreversible inhibitor of caspase-3 ( IC50=25nm), caspase-1 (IC50=50nM), caspase-8 (IC50=100nM) and caspase-9 (IC50=430nM). It protects neurotoxin-insulted neurons from apoptotic death, as well as displays minimal toxicity. In order to reduce hydrophobicity of the peptide and to facilitate the use in aqueous media the aspartyl residue of the inhibitor is not o-methylated. 

仅供研究使用。 我们不向患者出售。

化学信息

名称Q-VD-OPH
Iupac 化学名称(3S)-5-(2,6-Difluorophenoxy)-3-[[(2S)-3-Methyl-1-oxo-2-[(2-quinolinylcarbonyl)aMino]butyl]aMino]-4-oxo-pentanoic Acid 
同义词Q-VD-OPH 
英文同义词Q-VD-OPH 
分子式C26H25F2N3O6 
分子量513.8 
SmileFC1=C(OCC([C@H](CC(=O)O)NC([C@H](C(C)C)NC(=O)C2=NC3=CC=CC=C3C=C2)=O)=O)C(=CC=C1)F
InChiKeyOOBJCYKITXPCNS-REWPJTCUSA-N
InChiInChI=1S/C26H25F2N3O6/c1-14(2)23(31-25(35)19-11-10-15-6-3-4-9-18(15)29-19)26(36)30-20(12-22(33)34)21(32)13-37-24-16(27)7-5-8-17(24)28/h3-11,14,20,23H,12-13H2,1-2H3,(H,30,36)(H,31,35)(H,33,34)/t20-,23-/m0/s1
Cas号1135695-98-5
相关CAS号

订购信息

包装价格库存纯度备货期
大货询价询价询价
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外观性状Solid powder 
纯度98% by HPLC 
存储-20 ºC for 3 years 
可溶性Soluble in DMSO 
处理方式
运输条件Shipped under ambient temperature 
海关编码
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

16071010 - Q-VD-OPH | CAS 1135695-98-5

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