CX-4945(Silmitasertib)
编号: 52024
Cas号: 1009820-21-6
纯度: 98%
Silmitasertib (CX-4945) is a potent and selective orally bioavailable small molecule inhibitor of Casein kinase II (CK2). The antiproliferative activity of CX-4945 against cancer cells correlated with expression levels of the CK2α catalytic subunit. CX-4945 caused cell-cycle arrest and selectively induced apoptosis in cancer cells relative to normal cells.
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化学信息
| 名称 | CX-4945(Silmitasertib) |
|---|---|
| Iupac 化学名称 | 5-(3-chlorophenylamino)benzo[c][2,6]naphthyridine-8-carboxylic acid |
| 同义词 | CX-4945;Silmitasertib;CX4945;CX 4945 |
| 英文同义词 | CX-4945;Silmitasertib;CX4945;CX 4945 |
| 分子式 | C19H12ClN3O2 |
| 分子量 | 349.77 |
| Smile | ClC=1C=C(C=CC1)NC1=NC2=C(C3=CN=CC=C13)C=CC(=C2)C(=O)O |
| InChiKey | MUOKSQABCJCOPU-UHFFFAOYSA-N |
| InChi | InChI=1S/C19H12ClN3O2/c20-12-2-1-3-13(9-12)22-18-15-6-7-21-10-16(15)14-5-4-11(19(24)25)8-17(14)23-18/h1-10H,(H,22,23)(H,24,25) |
| Cas号 | 1009820-21-6 |
| 相关CAS号 |
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