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CX-4945(Silmitasertib) 编号 : 52024

化学信息

产品英文名称CX-4945(Silmitasertib)
Iupac 化学名称5-(3-chlorophenylamino)benzo[c][2,6]naphthyridine-8-carboxylic acid 
同义词CX-4945;Silmitasertib;CX4945;CX 4945 
英文同义词CX-4945;Silmitasertib;CX4945;CX 4945 
分子式C19H12ClN3O2 
分子量349.77 
SmileClC=1C=C(C=CC1)NC1=NC2=C(C3=CN=CC=C13)C=CC(=C2)C(=O)O
InChiKeyMUOKSQABCJCOPU-UHFFFAOYSA-N
InChiInChI=1S/C19H12ClN3O2/c20-12-2-1-3-13(9-12)22-18-15-6-7-21-10-16(15)14-5-4-11(19(24)25)8-17(14)23-18/h1-10H,(H,22,23)(H,24,25)
Cas1009820-21-6

技术数据

外观yellow solid 
纯度98% 
可溶性5mg/ml in DMSO 
存储3 years -20ºCpowder 6 months-80ºCin solvent 
运输条件Shipped under ambient temperature 
质量控制

产品详情

CX-4945 (Silmitasertib) is a potent and selective inhibitor of CK2 (casein kinase 2) with IC50 of 1 nM, less potent to Flt3, Pim1 and CDK1 (inactive in cell-based assay).  

结构

52024 - CX-4945(Silmitasertib) | CAS 1009820-21-6

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