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CYT387

Catalog No.: 52534
Cas No.: 1056634-68-4
Purity : 98% 
52534 - CYT387 | CAS 1056634-68-4

Catalog number : 52534

CAS number : 1056634-68-4

分子式 : C23H22N6O2 

分子量 : 414.46 

化学名称 : CYT387

Smile : c1cc(ccc1c2ccnc(n2)Nc3ccc(cc3)N4CCOCC4)C(=O)NCC#N

InChiKey : ZVHNDZWQTBEVRY-UHFFFAOYSA-N

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分子式C23H22N6O2 
分子量414.46 
纯度98% 
Smilec1cc(ccc1c2ccnc(n2)Nc3ccc(cc3)N4CCOCC4)C(=O)NCC#N
InChiKeyZVHNDZWQTBEVRY-UHFFFAOYSA-N
InChiInChI=1S/C23H22N6O2/c24-10-12-25-22(30)18-3-1-17(2-4-18)21-9-11-26-23(28-21)27-19-5-7-20(8-6-19)29-13-15-31-16-14-29/h1-9,11H,12-16H2,(H,25,30)(H,26,27,28)
MDLMFCD16038899
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CYT387(momelotinib) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, ~10-fold selectivity versus JAK3. 

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