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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
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TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
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Name Index T
Tanespimycin
(Catalog# : 16070805, Cas# :
75747-14-7
)
Tanespimycin, also known as 17-AAG, is an orally bioavailable, small-molecule inhibit
Taladegib
(Catalog# : 121414, Cas# :
1258861-20-9
)
Taladegib is a potent Hedgehog inhibitor with potential anticancer activity, which in
Tivantinib
(Catalog# : 16070802, Cas# :
905854-02-6
)
Tivantinib (ARQ-197) is an orally bioavailable small molecule inhibitor of c-Met with
TAK-580 (MLN2480)
(Catalog# : 16062203, Cas# :
1096708-71-2
)
TAK-580, also known as MLN2480, BIIB024, and AMG 2112819, is an oral, selective pan-R
trovirdine
(Catalog# : 16060302, Cas# :
149488-17-5
)
trovirdine
Taprenepag(CP-544326)
(Catalog# : 652601, Cas# :
752187-80-7
)
Taprenepag is the active metabolite of PF-04217329.
Trofinetide
(Catalog# : 032406, Cas# :
853400-76-7
)
Trofinetide is a glypromate (or Gly-Pro-Glu) analog and neuroprotectant.
Tyrosine kinase inhibitor
(Catalog# : 030302, Cas# :
1021950-26-4
)
Coming soon!
Tenalisib
(Catalog# : 012009, Cas# :
1639417-53-0 or 1693773-94-2
)
Tenalisib is a potent and selective dual PI3K/ inhibitor that inhibited growth of B-c
Tanzisertib
(Catalog# : 011903, Cas# :
899805-25-5
)
Tanzisertib is a potent, selective, and orally active JNK inhibitor with potential an
TH-302
(Catalog# : 011812, Cas# :
918633-87-1
)
TH-302 is selective hypoxia-activated prodrug targeting hypoxic regions of solid tumo
Tradipitant
(Catalog# : 011810, Cas# :
622370-35-8
)
Tradipitant is the 2nd generation neurokinin-1 receptor antagonist, which showed acti
TGN 255
(Catalog# : 011114, Cas# :
871576-03-3
)
Coming soon!
TAK-733
(Catalog# : 010813, Cas# :
1035555-63-5
)
TAK-733 is a potent and selective MEK allosteric site inhibitor for MEK1 with IC50 of
Tiotropium Bromide
(Catalog# : 010502, Cas# :
136310-93-5
)
Tiotropium Bromide is a muscarinic acetylcholine receptor (mAChR) antagonist that blo
Tetrabenazine
(Catalog# : 010501, Cas# :
58-46-8
)
Tetrabenazine is a VMAT-inhibitor used for treatment of hyperkinetic movement disorde
Tiotropium Bromide
(Catalog# : 010439, Cas# :
139404-48-1
)
Tiotropium Bromide hydrate is an anticholinergic and bronchodilator and a muscarinic
TAS-102
(Catalog# : 010437, Cas# :
733030-01-8
)
TAS-102 is an investigational drug candidate for metastatic colorectal cancer.
Tapentadol
(Catalog# : 010413, Cas# :
175591-23-8
)
Tapentadol is an Opioid Agonist. The mechanism of action of tapentadol is as an Opioi
Tapentadol hydrochloride
(Catalog# : 010407, Cas# :
175591-09-0
)
Tapentadol Hcl is a centrally acting oral analgesic with opioid and adrenergic activi
Testosterone
(Catalog# : 010405, Cas# :
58-22-0
)
Testosterone is a steroid hormone from the androgen group and is found in mammals, re
Tandutinib
(Catalog# : 123015, Cas# :
387867-13-2
)
Tandutinib is a potent FLT3 antagonist with IC50 of 0.22 M, also inhibits PDGFR and c
Tosedostat
(Catalog# : 123003, Cas# :
238750-77-1
)
Tosedostat is a proprietary orally bioavailable inhibitor of the M1 family of aminope
Trabectedin
(Catalog# : 122948, Cas# :
114899-77-3
)
Trabectedin is a novel antitumour agent of marine origin with potent antitumour activ
TBA-354
(Catalog# : 122934, Cas# :
1257426-19-9
)
TBA-354 is a potent anti-tuberculosis compound; maintains activity against Mycobacter
Terlipressin
(Catalog# : 122929, Cas# :
14636-12-5
)
Terlipressin is an analogue of vasopressin used as a vasoactive drug in the managemen
Tenapanor
(Catalog# : 122919, Cas# :
1234423-95-0
)
Tenapanoris an inhibitor of the sodium-proton exchanger NHE3. Thisantiporter protein
Terameprocol
(Catalog# : 122915, Cas# :
24150-24-1
)
Terameprocol is a synthetic tetra-methylated derivative of nordihydroguaiaretic acid
Tolvaptan
(Catalog# : 122814, Cas# :
150683-30-0
)
Tolvaptan is a selective, competitive arginine vasopressin receptor 2 antagonist with
TPT-260
(Catalog# : 122809, Cas# :
769856-81-7
)
TPT-260 is a thiophene thiourea derivative with molecule weight 260.00 in free base f
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
PLX8394
(Catalog# : 20613, Cas# :
1393466-87-9
)
PLX8394 is an orally bioavailable inhibitor of serine/threonine-protein kinase B-raf
Zelasudil
(Catalog# : 24014, Cas# :
2365193-22-0
)
Zelasudil is a potent, highly selective and orally-active inhibitor that targets Rho-
Ziftomenib ( KO-539 )
(Catalog# : 24013, Cas# :
2134675-36-6
)
Ziftomenib is an oral, potent, and selective small molecule inhibitor that targets th
Zunsemetinib
(Catalog# : 24012, Cas# :
1640282-42-3
)
Zunsemetinib is an investigational oral mitogen-activated protein kinase-activated pr
Zongertinib
(Catalog# : 24011, Cas# :
2728667-27-2
)
Zongertinib [BI 1810631] is a human epidermal growth factor receptor 2 (HER2) inhibit
Zasocitinib
(Catalog# : 24010, Cas# :
2272904-53-5
)
Zasocitinib is under development for the treatment of moderate to severe plaque psori
RNK-05047
(Catalog# : 24008, Cas# :
2503036-46-0
)
RNK-05047 is a PROTAC degrader of BRD4 which displays significant tumor growth inhibi
Asengeprast (FT011)
(Catalog# : 24009, Cas# :
1001288-58-9
)
Asengeprast (FT011) is an anti-fibrotic agent thatreduces mRNA expression of collagen
ERAS-801 ( JGK-068S )
(Catalog# : 20635, Cas# :
2490431-16-6
)
ERAS-801 ( JGK-068S ) is a potent EGFR inhibitor.
T-1095
(Catalog# : 24004, Cas# :
209746-59-8
)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).