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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
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Name Index T
TPO agonist 1
(Catalog# : 6111515, Cas# :
1033040-23-1
)
TPO agonist 1 can increase production of platelets by stimulating the TPO receptor in
TY-52156
(Catalog# : 61118, Cas# :
934369-14-9
)
TY-52156 is a potent S1P3 receptor antagonist in a competitive manner, and the Ki val
TCS-OX2-29
(Catalog# : 61117, Cas# :
372523-75-6
)
TCS-OX2-29 is a potent and selective OX2 receptor antagonist with IC50 of 40 nM. Disp
THZ1
(Catalog# : 6111013, Cas# :
1604810-83-4
)
THZ1 is a novel selective and potent covalent CDK7 inhibitor with IC50(binding affini
TZ9
(Catalog# : 611934, Cas# :
1002789-86-7
)
TZ9 is a novel inhibitor of Rad6 ubiquitin conjugating enzyme(E2 enzyme); inhibits MD
THZ1-R
(Catalog# : 611926, Cas# :
1621523-07-6
)
THZ1-R is a non-cysteine reactive analog, which displays diminished activity for CDK7
THZ1 Hydrochloride
(Catalog# : 611925)
THZ1 Hcl is a novel selective and potent covalent CDK7 inhibitor with IC50(binding af
TGR-1202 hydrochloride
(Catalog# : 611905, Cas# :
1532533-78-0
)
TGR-1202 hydrochloride is an orally available, next generation PI3Kdelta inhibitor, i
TDZD-8
(Catalog# : 161009029, Cas# :
327036-89-5
)
TDZD-8 protects the brain against I/R injury by inhibiting GSK-3beta activity. TDZD-8
Tideglusib
(Catalog# : 9028, Cas# :
865854-05-3
)
Tideglusib protects neural stem cells against NMDA receptor overactivation. Tideglusi
TWS-119
(Catalog# : 161009027, Cas# :
601514-19-6 (free base); 1507095-58-0 (2 TFA salt)
)
TWS119 could activate Wnt/-catenin pathway and up-regulate the expression of CD62L in
Triciribine
(Catalog# : 161009022, Cas# :
35943-35-2
)
Triciribine inhibits the phosphorylation, activation, and signalling of Akt-1, -2, an
Tacrolimus
(Catalog# : 161009006, Cas# :
104987-11-3
)
It is also used in a topical preparation in the treatment of atopic dermatitis (eczem
TG100713
(Catalog# : 160926017, Cas# :
925705-73-3
)
TG100713 is an inhibitor of PI3-kinase (IC50 values are 24, 50, 165 and 215 nM for PI
TG100-115
(Catalog# : 160926011, Cas# :
677297-51-7
)
TG100-115, inhibited PI3K and -(IC50 values of 83 and 235 nM, respectively), whereas
Taltirelin
(Catalog# : 16071029, Cas# :
103300-74-9
)
Taltirelin
TMP-195
(Catalog# : 16071020, Cas# :
1314891-22-9
)
TMP-195
TC-G 1008
(Catalog# : 16071003, Cas# :
1621175-65-2
)
TC-G 1008,
T-5224
(Catalog# : 16070909, Cas# :
530141-72-1
)
T-5224 is a selective inhibitor of c-Fos/activator protein-1. T-5224 ameliorates live
Tanespimycin
(Catalog# : 16070805, Cas# :
75747-14-7
)
Tanespimycin, also known as 17-AAG, is an orally bioavailable, small-molecule inhibit
Taladegib
(Catalog# : 121414, Cas# :
1258861-20-9
)
Taladegib is a potent Hedgehog inhibitor with potential anticancer activity, which in
Tivantinib
(Catalog# : 16070802, Cas# :
905854-02-6
)
Tivantinib (ARQ-197) is an orally bioavailable small molecule inhibitor of c-Met with
TAK-580 (MLN2480)
(Catalog# : 16062203, Cas# :
1096708-71-2
)
TAK-580, also known as MLN2480, BIIB024, and AMG 2112819, is an oral, selective pan-R
trovirdine
(Catalog# : 16060302, Cas# :
149488-17-5
)
trovirdine
Taprenepag(CP-544326)
(Catalog# : 652601, Cas# :
752187-80-7
)
Taprenepag is the active metabolite of PF-04217329.
Trofinetide
(Catalog# : 032406, Cas# :
853400-76-7
)
Trofinetide is a glypromate (or Gly-Pro-Glu) analog and neuroprotectant.
Tyrosine kinase inhibitor
(Catalog# : 030302, Cas# :
1021950-26-4
)
Coming soon!
Tenalisib
(Catalog# : 012009, Cas# :
1639417-53-0 or 1693773-94-2
)
Tenalisib is a potent and selective dual PI3K/ inhibitor that inhibited growth of B-c
Tanzisertib
(Catalog# : 011903, Cas# :
899805-25-5
)
Tanzisertib is a potent, selective, and orally active JNK inhibitor with potential an
TH-302
(Catalog# : 011812, Cas# :
918633-87-1
)
TH-302 is selective hypoxia-activated prodrug targeting hypoxic regions of solid tumo
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Dabogratinib ( TYRA-300 )
(Catalog# : 24073, Cas# :
2800223-30-5
)
Dabogratinib ( TYRA-300 ) is an Oral Selective FGFR3 Inhibitor (IC50 = 11 nM) for the
AF710B
(Catalog# : 25205, Cas# :
N/A
)
AF710B is a highly selective and potent allosteric agonist for M1 muscarinic and σ1
MAT2A inhibitor 5
(Catalog# : 25204, Cas# :
2957874-18-7
)
MAT2A inhibitor 5 has a high potency for inhibiting MAT2A and a remarkable selectivit
(Rac)-AF710B
(Catalog# : 24083, Cas# :
1235733-73-9
)
AF-710B is an agonist of sigma and M1 muscarinic receptors; AF710B is an enantiomer o
Flurpiridaz-nonradiolabeled
(Catalog# : 25203, Cas# :
863888-33-9
)
Flurpiridazis a promising novel cardiac PET imaging tracer formed by the radiolabelin
Flurpiridaz-Precursor
(Catalog# : 25202, Cas# :
863888-32-8
)
Flurpiridaz-Precursor in stock.
KL1333
(Catalog# : 25201, Cas# :
1800405-30-4
)
KL1333 is an orally available, small organic molecule that reacts with NAD(P)H:quinon
Palupiprant ( E7046 )
(Catalog# : 24055, Cas# :
1369489-71-3
)
E7046 is a potent and selective antagonist of the type 4 prostaglandin E2 (PGE2) rece
Oveporexton ( TAK-861 )
(Catalog# : 25194, Cas# :
2460722-04-5
)
Oveporexton isan oral small molecule selective orexin type-2 receptor (OX2R) agonist.
VT-3989
(Catalog# : 25200, Cas# :
2506273-81-8
)
VT3989, a first-in-class potent oral TEAD palmitoylation inhibitor, disrupts YAP tran