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TG100-115

Catalog No.: 160926011
Cas No.: 677297-51-7
Purity : 98% by HPLC 
160926011 - TG100-115 | CAS 677297-51-7

Catalog number : 160926011

CAS number : 677297-51-7

Molecular Formula : C18H14N6O2 

Molecular Weight : 346.34276 

Iupac Chemical Name : 3-[2,4-diamino-6-(3-hydroxyphenyl)pteridin-7-yl]phenol 

Smile : NC1=NC2=NC(=C(N=C2C(=N1)N)C1=CC(=CC=C1)O)C=1C=C(C=CC1)O

InChiKey : UJIAQDJKSXQLIT-UHFFFAOYSA-N

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SynonymsTG100115; TG-100115; TG 100115; TG-100-115; TG100-115 ; TG 100-115. 
Molecular FormulaC18H14N6O2 
Molecular Weight346.34276 
AppearanceSolid powder 
Purity98% by HPLC 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
SmileNC1=NC2=NC(=C(N=C2C(=N1)N)C1=CC(=CC=C1)O)C=1C=C(C=CC1)O
InChiKeyUJIAQDJKSXQLIT-UHFFFAOYSA-N
InChiInChI=1S/C18H14N6O2/c19-16-15-17(24-18(20)23-16)22-14(10-4-2-6-12(26)8-10)13(21-15)9-3-1-5-11(25)7-9/h1-8,25-26H,(H4,19,20,22,23,24)
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 TG100-115, inhibited PI3K  and -(IC50 values of 83 and 235 nM, respectively), whereas both PI3K and - were relatively unaffected (IC50 values>1 M). As a gauge of general specificity, TG100-115 was also assayed against a 133 protein kinase panel, none of which was inhibited at IC50 values<1 M. 

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