TCS-OX2-29
Catalog No: 61117
CAS Number: 372523-75-6
Purity: 98%
TCS-OX2-29 is a potent and selective OX2 receptor antagonist with IC50 of 40 nM. Displays >250-fold selectivity for OX2 over OX1.
TCS-OX2-29 shows selectivity for ion channels, and transporters (<30% inhibition at 10 M), which includes G-protein coupled receptors associated with food intake including galanin and neuripeptide Y.
TCS-OX2-29 Inhibits orexin A induced IP3 accumulation and ERK1/2 phosphorylation in CHO cells transfected with the OX2 receptor.
For research use only. We do not sell to patients.
Chemical Information
| Name | TCS-OX2-29 |
|---|---|
| Iupac Chemical Name | TCS-OX2-29 |
| Synonyms | TCS OX2 29 |
| Molecular Formula | C23H31N3O3 |
| Molecular Weight | 397.51 |
| Smile | CC(C)(C)[C@@H](C(=O)N1CCc2cc(c(cc2C1)OC)OC)NCc3ccncc3.Cl |
| InChiKey | NHKNHFJTMINMBP-ZMBIFBSDSA-N |
| InChi | InChI=1S/C23H31N3O3.ClH/c1-23(2,3)21(25-14-16-6-9-24-10-7-16)22(27)26-11-8-17-12-19(28-4)20(29-5)13-18(17)15-26;/h6-7,9-10,12-13,21,25H,8,11,14-15H2,1-5H3;1H/t21-;/m1./s1 |
| CAS Number | 372523-75-6 |
| MDL | MFCD12828766 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
