+86-27-65522453 sales@sun-shinechem.com


Catalog No.: 16070909
Cas No.: 530141-72-1
Purity : 98% by HPLC 
16070909 - T-5224 | CAS 530141-72-1

Catalog number : 16070909

CAS number : 530141-72-1

Molecular Formula : C29H27NO8 

Molecular Weight : 517.52658 

Iupac Chemical Name : 3-(5-(4-(cyclopentyloxy)-2-hydroxybenzoyl)-2-((3-hydroxybenzo[d]isoxazol-6-yl)methoxy)phenyl)propanoic acid 

Smile : C1(CCCC1)OC1=CC(=C(C(=O)C=2C=CC(=C(C2)CCC(=O)O)OCC2=CC3=C(C(=NO3)O)C=C2)C=C1)O


PackagingPriceAvailabilityPurityEstimated Shipping Time
Request Bulk Quote Download MSDSTel:+86-27-65522453 | Email:sales@sun-shinechem.com
SynonymsT5224; T-5224 
Molecular FormulaC29H27NO8 
Molecular Weight517.52658 
AppearanceSolid powder 
Purity98% by HPLC 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
Coming soon.
T-5224 is a selective inhibitor of c-Fos/activator protein-1. T-5224 ameliorates liver injury and improves survival through decreasing production of proinflammatory cytokines and chemokines in endotoxemic mice. T-5224 has been investigated in phase II human clinical trials. T-5224 may be a promising new treatment for septic kidney injury. Activator protein 1 (AP-1) is a pivotal transcription factor that regulates a wide range of cellular processes including proliferation, apoptosis, differentiation, survival, cell migration, and transformation. Accumulating evidence supports that AP-1 plays an important role in several severe disorders including cancer, fibrosis, and organ injury, as well as inflammatory disorders such as asthma, psoriasis, and rheumatoid arthritis. 

530141-72-1 - Request Bulk Quote

530141-72-1 - Request Bulk Quote